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Ampho-B 50mg Injection

Salt Composition: AMPHOTERICIN B

₹236.00₹296.00

Inclusive of all taxes

Categories: Others

Conditions: Antifungal

Product Introduction

Ampho-B 50mg Injection is an antifungal medication containing amphotericin B as its active ingredient. It is used to treat fungal infections affecting one or more deep body organs. It is also indicated for treatment of suspected fungal infections in patients with fever and neutropenia (low white blood cell count). This injection is also used to treat visceral leishmaniasis, a parasitic disease in certain patients.

Do not receive this injection if you are allergic to amphotericin B or any other ingredients in the medicine. Inform your doctor if you have severe allergic reactions, kidney or liver problems, or if you are undergoing dialysis. Notify your doctor if you have low potassium levels.

This injection may cause severe infusion reactions including flushing, itching, nausea, swelling of the face, mouth, tongue, and airways, and difficulty breathing. Inform your doctor immediately if you experience any of these symptoms.

Before your first treatment, your doctor may administer a small test dose of Ampho-B 50mg Injection to assess for allergic reactions. This medicine contains sugar in each vial; inform your doctor if you have diabetes. Notify your doctor if you are pregnant or breastfeeding before starting treatment.

Your doctor will determine the appropriate dose and quantity of this medicine based on your medical condition.

Uses

Treatment of fungal infections

How it works

Ampho-B 50mg Injection binds primarily to ergosterol in sensitive fungi cell membranes, causing membrane permeability changes that result in leakage of intracellular contents and cell death.

How to Use

A doctor or nurse in a hospital or clinic setting will give it to you. It is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Serious allergic reactions (sudden onset of itching, rash or hives on the skin, shortness of breath and wheezing) Increased blood sugar levels Decreased potassium levels Shortness of breath, Fever, chills, or shivering Common Headache Dizziness Diarrhea Nausea Indigestion Abdominal Pain

Expert Tips

Ampho-B 50mg Injection may cause damage to the kidney. Inform your doctor if you have kidney problems. It may be necessary to continue this medication for several weeks to several months to treat certain infections. Stopping the medication too early may result in a return of the infection. Tell your doctor if your condition lasts or gets worse.

References

  1. Gilead Sciences International Ltd, Electronic medicines compendium (EMC), [ Revised on Sept 2020] [ Accessed on 11th June 2023], https://www.medicines.org.uk/emc/files/pil.1022.pdf
  2. Gilead Sciences, Inc, US Food and Drug Administration, [ Revised on Oct 2008] [ Accessed on 11th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050740s016lbl.pdf
  3. Lifecare innovations; [Accessed on June 12th 2023]; https://www.lifecareinnovations.com/mucormycosis.php
  4. Falah Hasan et al; Topical Amphomul 50mg Injection formulas: Promising new application; [Published on August 2019]; [Accessed on June 11th 2023]; https://www.researchgate.net/publication/334882993_Topical_Amphotericin_B_formulas_Promising_new_application
  5. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Chemotherapy of protozoal infections, 12th edition, 2011, 1424.
  6. KD Tripathi, Essentials of Medical Pharmacology, Antifungal drugs, 7th edition, 2013, 787-788.

Safety Advice

Pregnancy: Consult your doctor If you are pregnant, suspecting, or planning for the pregnancy, consult your physician for more advice before taking Ampho-B 50mg Injection. Physicians may prescribe this medicine only when it is needed.

Lungs: Consult your doctor It is unknown whether Ampho-B 50mg Injection is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.

Breastfeeding: Consult your doctor If you are a breastfeeding mother, it's important to consult with your doctor before taking Ampho-B 50mg Injection.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS