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Apnat 60mg Tablet

Salt Composition: APALUTAMIDE

₹26250.00₹32812.50

Inclusive of all taxes

Apnat 60mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Apnat 60 mg contains Apalutamide as its active ingredient. It is an anti-cancer medication that belongs to the class of androgen receptor inhibitors. It is indicated for treating patients with certain types of prostate cancer whose cancer has spread to other parts of the body and remains responsive to medical or surgical treatment that lowers testosterone (male reproductive hormone), or whose cancer has not spread to other parts of the body and is no longer responsive to medical or surgical treatment that lowers testosterone. Apnat 60 mg works by blocking the effects of androgen (male reproductive hormone) to stop the growth or spread of cancer cells. Inform your doctor if you experience any symptoms of chest pain, indigestion, heart attack, difficulty walking, and numbness in the face and body. It is not recommended for pregnant women as it may cause harm to the unborn baby. This medication may be taken with or without food. This medicine may cause fertility problems in males. Males should not father children or donate sperm during treatment and for 3 months after the final dose. Use effective contraceptive methods.

Uses

Metastatic castration-sensitive prostate cancer. Non-metastatic castration-resistant prostate cancer.

How it works

Apnat 60 mg is a selective androgen receptor (AR) inhibitor that binds directly to the androgen receptor binding domain. It inhibits protein transportation in the nucleus, DNA binding, and AR-mediated transcription. Treatment with this medicine reduces cancer cell growth and increases cell death, resulting in effective anticancer activity.

How to Use

Apnat 60 mg is an orally administered drug. Take medicine as informed by your physician. It is usually taken with or without food once a day. Take medicine at around the same time every day. Swallow the tablets whole; do not split, chew, or crush them. Do not stop taking this without talking to your doctor.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common: Increased cholesterol levels Increased blood pressure Swelling in lower legs or hands Rash and reddening of the skin Decreased body weight and loss of appetite Diarrhea and nausea Muscle pain Tiredness and dizziness Serious: Anemia Heart disease, stroke or mini-stroke Increased blood sugar levels Decreased white blood cells Fractures of bones Seizures and cerebrovascular events Severe skin reactions Falls

Expert Tips

Inform your physician if you have any heart, kidney, liver, or lung disorders before the treatment. Your doctor might give you other medicines unless you had surgery to lower the amount of testosterone in your body. Continue taking this medicine with all the other medications that your doctor prescribes. Apnat 60 mg may cause birth defects if your male partner uses this medicine while planning for pregnancy. Use effective birth control pills or methods during the treatment and for 3 months after the last dose. Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Do not stop using this medicine, even for a short time, without first asking your doctor.

References

  1. HIGHLIGHTS OF PRESCRIBING INFORMATION. (2019). [online] Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210951s001lbl.pdf [Accessed 13 Jan. 2023].
  2. 2021 (2021). Apalutamide: MedlinePlus Drug Information . [online] medlineplus.gov. Available at: https://medlineplus.gov/druginfo/meds/a618018.html [Accessed 13 Jan. 2023].
  3. PATIENT INFORMATION ERLEADA ® (er lee’dah) (apalutamide). (2022). [online] Available at: https://www.janssenlabels.com/package-insert/product-patient-information/ERLEADA-ppi.pdf [Accessed 13 Jan. 2023].
  4. www.cancer.gov. (2018). Apalutamide - National Cancer Institute . [online] Available at: https://www.cancer.gov/about-cancer/treatment/drugs/apalutamide [Accessed 13 Jan. 2023].

Safety Advice

Pregnancy: unsafe You should know that apatite 60 mg is only for use in men. This drug is not recommended for women, especially if they are or may become pregnant, because it may cause harm to the unborn baby and result in loss of pregnancy. It is better to discuss with a doctor to use of an effective contraceptive method during the treatment and for 3 months after the last dose if your male partner is consuming Apnat 60 mg. It is recommended to consult your physician if you are pregnant already or suspect pregnancy.

Lungs: Consult your doctor It is unknown whether Apnat 60 mg can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Apnat 60 mg is not indicated in females. It is unknown whether this medicine is excreted in human milk. It is impossible to rule out a risk for the nursing infant. This medicine should not be used during breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS