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Aprelieva 150mg Injection

Salt Composition: FOSAPREPITANT DIMEGLUMINE

₹1360.00₹2437.50

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Aprelieva 150mg injection is used to treat nausea and vomiting. It is commonly administered as an injection to control acute and delayed nausea and vomiting associated with cancer treatment, including high-dose cisplatin (highly emetogenic) and moderately emetogenic cancer chemotherapy. Oral contraceptives may lose efficacy during treatment with Aprelieva 150mg injection. Concomitant administration with warfarin significantly alters blood clotting time, so patients on chronic warfarin therapy require monitoring before initiating Aprelieva 150mg injection. It is contraindicated in individuals with hypersensitivity to the drug. The dosage regimen includes oral dexamethasone in treatment.

Uses

High emetogenic cancer chemotherapy Moderately emetogenic cancer chemotherapy

How it works

It works by acting on the receptors responsible for nausea and vomiting, antagonising the substances involved in the same.

How to Use

It will be administered intravenously by health care professionals. The reconstituted or diluted solutions should be checked for the presence of precipitate or cloudiness.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Skin blistering, peeling Low white blood cell count Anemia Anaphylactic reactions Urinary tract infection Pain in extremity Abnormal physical weakness Infection Nerve damage Common: Fatigue Diarrhea Indigestion Anemia Rash, urticaria Itching

Expert Tips

This injection should be administered only by the doctor or nurse, and do not self-administer this injection. Inform the doctor if the patient has any history of allergic reactions, liver or kidney problems, and other medication taken for different medical conditions. Consult the doctor if the patient is planning for pregnancy or breastfeeding mother before taking this medication. Avoid driving and handling heavy machinery as it causes dizziness. Patients may feel a lack of concentration and alertness.

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
  2. Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date Feb 2016], [Accessed date 2nd April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/022023s014lbl.pdf
  3. National Cancer Institute, [Accessed date 2nd April 2021] + https://www.cancer.gov/publications/dictionaries/cancer-terms/def/fosaprepitant-dimeglumine

Safety Advice

Pregnancy: Consult your doctor There are no established adverse effects of the Aprelieva 150 mg injection during pregnancy. It is advisable to take it only under specialist advice on requirements. Consult your doctor about the potential risks of this medication.

Lungs: Consult your doctor It is unknown whether Amitant 150 mg injection is safe when administered in lung failure patients. Please consult the doctor if you have any lung problems.

Breastfeeding: Consult your doctor Inform your physician if you are breastfeeding before taking this medicine.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS