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Apremex 150mg Capsule

Salt Composition: MEXILETINE

₹656.00₹703.13

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Apremex 150mg Capsule

Categories: Cardiology

Conditions: Hypertension

Product Introduction

Apremex 150mg Capsule is an antiarrhythmic medicine containing the active pharmaceutical ingredient Mexiletine. This medication is used to treat irregular heart rhythms, also known as arrhythmias. It also helps to treat the symptoms of myotonia in adults who have non-dystrophic myotonic disorders (conditions that result from genetic defects that affect muscle function). These disorders are mainly caused by muscle-related symptoms rather than being caused by a specific type of muscular dystrophy. Myotonia is a medical term that refers to a condition where muscles have difficulty relaxing after they've been used. This can lead to stiffness or delayed relaxation of muscles.

If you have had a heart attack (myocardial infarction), this drug is contraindicated for you. Before beginning treatment with Apremex 150mg, inform your doctor if you have any heart, liver, or kidney problems, low or high potassium blood levels, low magnesium blood levels, or epilepsy. This drug can affect the nervous system and may need to be used cautiously in individuals with seizure disorders. If you have an allergy to any local anaesthetics, which are a class of medications that numb a specific area of the body, you should not take this medicine. The use of this drug is not advised for children and adults under 18 years of age.

Apremex 150mg substitutes may include other brands containing Mexiletine 150mg, but only your doctor can recommend the right alternative. While taking this medicine, reducing your caffeine intake by half is recommended. This is because Apremex 150mg can increase the levels of caffeine in your blood. High levels of caffeine can lead to side effects like jitteriness, increased heart rate, and other adverse effects. By reducing your caffeine intake, you can help prevent these interactions.

Consult your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. This drug can pass into breast milk. Therefore, breastfeeding is not recommended while undergoing treatment with this drug.

Uses

Apremex uses are: Treatment of arrhythmias Non-dystrophic myotonic disorders

How it works

Apremex 150mg Capsule works by blocking sodium channels in heart and nerve cells. This action helps prevent certain signals in the heart that could lead to an irregular heartbeat. As a result, this medication restores a normal heart rhythm, promoting a regular and steady heartbeat.

How to Use

Take the Apremex 150mg Capsule as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct Apremex 150mg dosage and duration based on age, body weight, and disease condition. Only stop taking the capsule if your doctor advises you to stop.

Side Effects

Apremex 150mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Severe Allergic reaction Convulsions (fits) Speech disorders Liver injury Oesophagus injury Pulmonary fibrosis Confusion Double vision Disorders of heart rhythm Collapse Slowed heart rate Common Vertigo Vomiting Weakness Abdominal pain Acne Blurred vision Chest pain Low blood pressure Fatigue Flushing Headache Increased heart rate Insomnia Nausea Pain in extremities Paresthesia Sleepiness Tremors

References

  1. Lupin Europe GmbH, Electronic Medicines Compendium (EMC), [Revised on 2nd Jun 2021] [Accessed on 29th August 2023], https://www.medicines.org.uk/emc/files/pil.9838.pdf
  2. Danbury; US Food and Drug Administration; [Published on 1998] [Accessed on 29th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/anda/98/74865ap_appltr_prntlbl.pdf
  3. S Singh et al; Mexiletine; NCBI Bookshelf; [Revised on 19th May 2021] [Accessed on 29th August 2023], https://www.ncbi.nlm.nih.gov/books/NBK519045/
  4. KD Tripathi, Antiarrhythmic Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 570-583.
  5. Robert D. Harvey, Augustus O. Grant, Agents Used in Cardiac Arrhythmias, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 228-253.

Safety Advice

Pregnancy: Consult your doctor If you are pregnant, suspecting, or planning for the pregnancy, report to your doctor before starting the treatment with Apremex 150mg Capsule.

Lungs: Consult your doctor Apremex 150mg Capsule should be cautiously used in patients with lung diseases. Inform your physician if you have lung disease before starting the treatment.

Breastfeeding: unsafe Apremex 150mg Capsule can pass into breast milk. Therefore, breastfeeding is not recommended while undergoing treatment with this drug.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS