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Arbaz 60mg Injection
Salt Composition: CABAZITAXEL
- Manufacturer: ADLEY FORMULATIONS
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 60MG
- Prescription Required
- Storage: Store Arbaz 60mg Injection in the original package at room temperature (30°C). Do not refrigerate.
₹7969.00₹12944.63
Inclusive of all taxes
Product Introduction
Arbaz 60mg Injection contains the active constituent cabazitaxel. It is an anticancer medicine used with steroid medicine prednisone or prednisolone to treat patients with hormone-refractory metastatic prostate cancer that has progressed after treatment with other anticancer medications, including docetaxel. Cancer is an abnormal and uncontrolled multiplication of cells. Many early-stage prostate cancers require normal testosterone (male hormone) levels to grow. In hormone-refractory metastatic prostate cancer, cancer continues to grow even when the amount of testosterone in the body is reduced to low levels. This medicine should not be used if you have severe abnormal liver function or have recently been vaccinated against yellow fever. Its major toxicities include myelosuppression, neurotoxicity, and allergic reactions. Neutropenia is the most common adverse reaction of Arbaz 60mg Injection. Monitoring of complete blood counts is essential on a weekly basis during cycle 1 and before each treatment cycle thereafter so that the dose can be adjusted, if needed. Vaccination with a live attenuated vaccine should be avoided in patients receiving Arbaz Injection; instead, killed or inactivated vaccines can be administered. Consult your doctor before using this medication if you are pregnant or plan to become pregnant. This drug is unsafe to use during pregnancy as it causes harm to an unborn fetus. Your healthcare practitioner will conduct a pregnancy test before you start treatment with Arbaz 60mg Injection. Discuss with your doctor effective birth control methods and use them for at least two weeks following the last dose. Avoid breastfeeding your baby while on treatment as it is unknown if this drug passes into the breast milk. Arbaz 60mg Injection price in India varies by seller and location.
Uses
Advanced prostate cancer .
How it works
It is a mitotic inhibitor that works by disrupting the normal process of cell division. This interferes with the microtubules that help to form the cell's cytoskeleton. Microtubules are essential for the normal process of cell division, as they help to pull apart the chromosomes during mitosis. By inhibiting microtubules, Arbaz 60mg Injection prevents the cancer cells from dividing properly and ultimately leads to their death.
Side Effects
The Arbaz injection side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Low white blood cells Infection (fever, cough, muscle aches, burning on urination) Severe allergic reactions (rash, itching, breathing problems, swelling of face, chest, or throat tightness) Kidney damage Severe stomach pain Common: Low red blood cell count Low blood platelet count Constipation Back pain, joint pain Decreased appetite Hair loss Numbness, burning, tingling, or decreased sensation in your feet or hands Taste change Headache, dizziness Inflammation of mouth Blood in urine
Expert Tips
Drink at least two litres of fluids every day when you are having diarrhoea. Avoid milk, dairy products, high fibre food or spicy food while you are having diarrhoea. Rinsing your mouth with an alcohol-free mouth gargle or salt water may help reduce chances of infections like mouth ulcers. Risk of infection can occur as this drug can reduce the WBC count in your blood, so it is advised to avoid crowds and people who are sick, wash your hands after toileting. You must not become pregnant during treatment and must use an effective method of contraception. If pregnancy occurs during your treatment, you must inform your doctor immediately. This drug may make you dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. If you are addicted to alcohol, have liver disease or epilepsy, talk to your doctor before taking this medicine.
References
- Annex I summary of Product Characteristics - European Medicines Agency. Available at: https://www.ema.europa.eu/en/documents/product-information/jevtana-epar-product-information_en.pdf [ Accessed on 29th March 2023]
- Bertram.G.Katzung, Basic and Clinical Pharmacology, Cancer Chemotherapy, 14th edition, 2017, 963.
Safety Advice
Pregnancy: unsafe It is unsafe to use during pregnancy whether Arbaz 60mg Injection can be taken during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is unknown whether Arbaz 60mg Injection can be used for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe It is unsafe to breastfeed during the treatment with this Arbaz 60mg Injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.