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Arganat 250mg Injection

Salt Composition: ARGATROBAN

₹7493.00₹9365.63

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Arganat 250mg Injection

Categories: Cardiology

Conditions: Anticoagulants

Product Introduction

Arganat 250mg injection is an anticoagulant containing argatroban as its active ingredient. It is used in the treatment of heparin-induced thrombocytopenia (HIT), a rare but serious condition that can develop following exposure to heparin, a commonly used blood thinner. The medication works by binding to the active site of thrombin, an enzyme essential for blood clot formation. This binding prevents thrombin from activating other clotting factors and forming clots.

Arganat 250mg injection should not be used if you are allergic to argatroban or any other ingredients in the medication. Avoid use if you have uncontrolled bleeding or severely impaired liver function. Inform your doctor if you have an increased risk of bleeding or have recently received injections or infusions of other anticoagulants such as heparin. This medicine is not recommended for use in children under 18 years of age.

Uses

Heparin-induced thrombocytopenia. Patients with a risk of heparin-induced thrombocytopenia undergoing percutaneous coronary intervention (PCI).

How it works

Arganat 250mg injection works by binding to the active site of thrombin, an enzyme that is essential for blood clot formation. This prevents thrombin from activating other clotting factors and forming clots.

How to Use

Arganat 250mg injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered in a vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Bleeding or bruising Blood in urine or stools Vomiting or coughing up blood Black stools Difficulty in breathing Cold sweaty skin Dry mouth Dilated pupils and/or weak rapid pulse Common Anaemia Blood clotting Purpura bleeding (numerous small bleeding in the skin and mucus membranes) Nausea

Expert Tips

Patients with liver conditions should take Arganat 250mg injection cautiously and inform their doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. If you have HIT type II, there is a higher chance of developing dangerous blood clots in your body that can lead to heart attacks, strokes, breathing difficulties, and issues with blood flow in your limbs. This medicine can help prevent these problems from occurring or getting worse. Do not breastfeed while taking Arganat 250mg injection unless your doctor advises. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.

References

  1. Central Pharma (Contract Packing) Limited, Electronic Medicines Compendium (EMC), [Revised on March 2021] [Accessed on 13th July 2023], Novastan Multidos conc f sol f inf ENG (medicines.org.uk)
  2. KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting Coagulation, bleeding and Thrombosis, 7th edition, 2013, 620.
  3. GlaxoSmithKline, US Food and Drug Administration, [ Accessed on 13th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020883s014lbl.pdf

Safety Advice

Pregnancy: Consult your doctor It is unknown whether Arganat 250mg injection is harmful to the unborn baby. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant.

Lungs: Consult your doctor It is unknown whether Arganat 250mg injection is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: Consult your doctor Taking Arganat 250mg injection while breastfeeding may be unsafe because it may affect the child. Inform your doctor if you are breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS