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Arnoza 100mg Tablet

Salt Composition: SACUBITRIL,VALSARTAN

₹366.00₹430.31

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Arnoza 100mg Tablet

Categories: Cardiology

Conditions: Heart Disorder

Product Introduction

Arnoza 100mg Tablet contains a combination of two active ingredients, Sacubitril and Valsartan, and belongs to a group of medicines known as angiotensin receptor-neprilysin inhibitors (ARNIs). It is used in adults for the treatment of chronic heart failure and is commonly prescribed along with other medications to reduce the likelihood of hospitalization and death associated with certain types of heart failure.

Do not take Arnoza 100mg Tablet if you are allergic to Sacubitril, Valsartan, or any of the other ingredients present in the formulation. This medicine should also be avoided by individuals who have a history of angioedema, a serious allergic reaction that causes swelling of the face, lips, tongue, or throat and may lead to breathing difficulties.

The tablet should not be used in patients with diabetes or kidney impairment who are taking blood pressure-lowering medicines containing Aliskiren. It is also contraindicated in individuals with severe liver disease and in women who are pregnant or breastfeeding.

Before starting treatment, inform your doctor about all medications you are currently taking, especially those used for heart conditions. You should also tell your healthcare provider if you suffer from low blood pressure, severe kidney problems, dehydration, liver disorders, hallucinations, or disturbances in sleep patterns.

Uses

To reduce the risk of cardiovascular death and hospitalization in adults with heart failure.

How it works

Sacubitril is a prodrug metabolized to the active metabolite, which inhibits neprilysin, thereby increasing levels of peptides (such as natriuretic peptides). It works to help control blood volume. Valsartan is an angiotensin receptor blocker that selectively blocks the AT1 receptor and inhibits angiotensin-II-dependent aldosterone release. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

How to Use

Always take this medicine exactly as your doctor or pharmacist has told you. Your physician will decide the dose and duration of the treatment based on your disease severity and other factors. Swallow the tablets with a glass of water. You can take Arnoza 100mg Tablet with or without food. Do not crush, chew, or split the tablets.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Low blood pressure Increased potassium levels Dizziness Serious Kidney damage Angioedema (swelling of the face, lips, tongue and throat, and difficulties in breathing)

Expert Tips

It is advisable to take your medicine at the same time each day. However, if you forget to take a dose, you should take the next one at the scheduled time. Do not take a double dose to make up for a forgotten tablet. Inform your physician if you have kidney problems before initiating the therapy. This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel dizzy or lightheaded. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

References

  1. Novartis Pharmaceuticals UK Ltd, Electronic Medicines Compendium(EMC), [Revised on June 2023 [Accessed on 14th June 2023], https://www.medicines.org.uk/emc/files/pil.5074.pdf
  2. Novartis, US Food and Drug Administration, [Revised on February 2021] [Accessed on 14th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/207620s018lbl.pdf
  3. KD Tripathi, Cardiac Glycosides and Drugs for Heart Failure, Essentials of Medical Pharmacology, 8th Edition, 2019, 556-569.
  4. Ian A. Reid, Vasoactive Peptides, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 300-320.

Safety Advice

Pregnancy: unsafe Do not take Arnoza 100mg Tablet if you are pregnant because it may cause harm to the unborn baby. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Lungs: Consult your doctor It is unknown whether Arnoza 100mg Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Arnoza 100mg Tablet because the medicine passes into the breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS