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Avplex 30mg Capsule

Salt Composition: APREMILAST

₹57.00₹65.63

Inclusive of all taxes

Categories: Dermatology

Conditions: Skin Care

Product Introduction

Avplex 30mg Capsule contains apremilast as the active component. It is indicated for the treatment of moderate to severe plaque psoriasis, a chronic autoimmune condition characterised by patches of abnormal skin. It may help reduce redness, scaling, and thickness of affected skin. It is also used to treat active psoriatic arthritis, a type of arthritis that affects some patients with psoriasis. This medication should not be used in individuals with known hypersensitivity or allergic reaction to apremilast or its components. It is associated with risks to the developing fetus and is contraindicated during pregnancy. Dosage adjustment of Avplex 30mg Capsule is required in patients with severe renal impairment because the drug is primarily excreted through the kidneys. There is limited information on the use of Avplex 30mg Capsule in the elderly population. Therefore, caution should be exercised in older adults, and dosage may require adjustment based on individual health conditions and renal function. It has not been studied in children under 18 years of age, and its safety and efficacy in this population have not been established.

Uses

Avplex 30mg Capsule is used in the treatment of the following: Plaque psoriasis Psoriatic arthritis

How it works

Avplex 30mg Capsule works by inhibiting an enzyme called phosphodiesterase 4 (PDE4), which regulates the production of certain inflammatory mediators. Reducing the activity of PDE4 helps to decrease the levels of these inflammatory mediators, thereby alleviating the symptoms associated with psoriasis and psoriatic arthritis.

How to Use

Avplex 30mg Capsule is administered orally in the form of tablets. It is taken orally with or without food, as directed by a healthcare professional. The recommended starting dosage and any necessary dose adjustments are determined based on the specific condition being treated and the individual patient's response to the medication.

Side Effects

Avplex 30mg Capsule causes some side effects like all medications, although not everyone will experience them. Serious side effects of Avplex 30mg Capsule are: Mood and mental health Gastrointestinal disturbances Allergic reactions Common side effects of Avplex 30mg Capsule are: Gastrointestinal effects Neurological effects Respiratory tract infections General symptoms

Expert Tips

Be cautious if you have a history of depression or mood disorders before taking Avplex 30mg Capsules. Report any changes in mood or behavior to your healthcare provider. Watch for gastrointestinal issues like diarrhea or nausea, and stay hydrated. Inform your doctor if you experience severe or persistent symptoms. Keep an eye on your weight while taking Avplex 30mg Capsules, as it may lead to weight loss. Report any significant or unexplained weight changes to your healthcare provider. Be vigilant for signs of infection, such as fever or persistent cough, and promptly report any concerns to your doctor. Avoid live vaccinations while on this medication, which may affect your immune response. Consult your healthcare provider before receiving any vaccines. Use it with caution if you have a history of liver or kidney problems, and follow your doctor's instructions for regular monitoring. Seek medical attention immediately if you notice any signs of allergic reactions, such as rash or swelling. Stick to the prescribed dosage. Do not stop taking it without consulting your healthcare provider. Be aware of any potential side effects and communicate any concerns promptly.

References

  1. 1. Amgen Ltd, Electronic medicines compendium (EMC), [Revised on 30th Jun 2021] [Accessed on 19th Oct 2023], https://www.medicines.org.uk/emc/product/3648/smpc#gref 2. US Food and Drug Administration, [Revised on Dec 2021 ] [Accessed on 19th 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/205437s011lbl.pdf

Safety Advice

Pregnancy: unsafe Avplex 30mg Capsules are unsafe during pregnancy due to the potential risks to the developing fetus.

Lungs: Consult your doctor Consult your healthcare provider if you have a history of lung conditions before using Avplex 30mg Capsules.

Breastfeeding: unsafe Avplex 30mg Capsules are unsafe if you are breastfeeding as it may pass into human milk, and there is a potential risk to the nursing infant.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS