Axentri 150mg Tablet

Axentri 150mg Tablet is an antiretroviral drug belonging to the chemokine receptor antagonist category, containing the active ingredient Maraviroc. It is used to treat CCR5-tropic human immunodeficiency virus type 1 (HIV-1) infection only. HIV infection spreads mainly through sexual contact with individuals who have the infection or through transfer of infected blood, such as by sharing injection needles. This drug must be taken in combination with other medicines used to treat HIV infection.

This drug is contraindicated in patients with severe renal impairment, as it may have altered drug clearance, which primarily affects the efficacy and safety of the medicine. Dose adjustment is necessary for such conditions. The liver metabolizes this medicine, specifically through the cytochrome P450 enzyme. In patients with liver impairment, the clearance of Axentri 150mg Tablet may be reduced, leading to increased drug concentrations in the bloodstream. Due to higher concentration, caution should be taken when administering the drug to patients with liver impairment. The dosage of this drug may need to be adjusted by your doctor, or it may need to be used with extra monitoring in these patients to ensure its safety and efficacy.

During the early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, immune reconstitution syndrome, can occur after starting the drug or other antiretroviral therapies. Monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual.

Healthcare professionals must carefully monitor patients taking this drug for any signs or symptoms of skin or hypersensitivity reactions, such as rash, blistering, or mucosal lesions. If a severe reaction is suspected, this medicine should be immediately discontinued and appropriate medical treatment initiated. Patients are advised to report any skin or hypersensitivity reactions to their healthcare provider and to seek medical emergency immediately if they experience any symptoms of a severe reaction.

Inform your doctor immediately about all medications you have been taking recently, including herbal and supplements, before taking Axentri 150mg Tablet.

Human Immunodeficiency Virus (HIV)

Axentri 150mg Tablet blocks a receptor named CCR5, which HIV uses to enter and infect your blood cells. This drug mainly prevents HIV from binding to and entering the CD4+ T cells, inhibiting the virus's ability to replicate and spread.

It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take a Axentri 150mg Tablet as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, or crush the tablet. Swallow the whole tablet with water.

Side Effects: Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Swelling of the face, lips, or tongue Difficulty breathing Widespread skin rash Fever (high temperature) Blisters and peeling skin, particularly around the mouth, nose, eyes, and genitals. Common Diarrhea Stomach ache Loss of appetite Headache Sleeping problems Depression Feeling weak or lack of energy Anaemia Increase in liver enzymes

To prevent the spread of HIV infection, avoid sharing needles or syringes, which can transmit HIV-1 infections easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items like toothbrushes, razor blades, or anything that can have blood or body fluids on them should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus.