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Azacbuzz 100mg Injection
Salt Composition: AZACITIDINE
- Manufacturer: JASGUR LIFE SCIENCES LLP
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 100MG
- Prescription Required
- Storage: Store at 25°C. Keep out of reach of children.
₹2016.00₹4007.81
Inclusive of all taxes
Product Introduction
Azacbuzz 100mg Injection contains the active ingredient Azacitidine. It is indicated for treatment of adults with Myelodysplastic Syndrome (MDS), chronic myelomonocytic leukaemia, and Acute Myeloid Leukaemia (AML) who are ineligible for stem cell transplant.
In Myelodysplastic Syndrome, the bone marrow fails to produce healthy blood cells due to impaired function. Acute Myeloid Leukaemia is a bone marrow malignancy characterised by release of immature blood cells into the bloodstream. Chronic myelomonocytic leukaemia is a rare blood malignancy marked by elevated numbers of monocytes among white blood cells.
Uses
This medicine is indicated to treat the following conditions: Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant High-risk Myelodysplastic syndrome (MDS) Chronic myelomonocytic leukemia.
How it works
Azacbuzz 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.
How to Use
Take Azacbuzz 100mg Injection only under the supervision of your physician. Your physician will decide the dose based on your height, weight and general condition. Azacbuzz 100mg Injection shall be given under the skin of your thigh, stomach or upper arm.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Drowsiness Shivering Jaundice Stomach bloating Unusual bleeding or bruising Reduced urination Increased thirst Dizziness Confusion Chest pain Breathlessness Allergies Common: Disturbances in the blood count (RBC, WBC, Platelets) Nausea, vomiting, diarrhea Constipation Tiredness Skin reaction like redness and pain at the site of injection Decreased appetite Dizziness Pain in extremities Joint pain Stomach pain Headache Sore nose and throat Rashes and bruising
Expert Tips
Inform the doctor if the patient has any allergy reactions, respiratory problems,kidney, liver, heart problems and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breast feeding mothers as this medicine causes harmful effects in the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight and general condition. It is administered under the skin of your thigh, stomach or upper arm.
References
- K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741, [Accessed on 5th Apr 2021] https://www.researchgate.net/publication/7094896_Transcriptional_repression_in_eukaryotes_Repressors_and_repression_mechanisms
- Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018 [Accessed on 3rd Apr 2021] https://bmchematol.biomedcentral.com/articles/10.1186/s12878-017-0094-8
- Bristol-Myers Squibb, Electronic Medicines Compendium (EMC), [Revised on Oct 2021] [Accessed on 2nd Dec 2021], https://www.medicines.org.uk/emc/files/pil.6468.pdf
- Leukaemia Care, [Revised on Jul 2020] [Accessed on 2nd Dec 2021], https://media.leukaemiacare.org.uk/wp-content/uploads/Chronic-Myelomonocytic-Leukaemia-CMML-Web-Version.pdf
Safety Advice
Pregnancy: unsafe This medicine is not intended for use during pregnancy. Talk to your physician if you are pregnant or think you could be pregnant.
Lungs: Consult your doctor Inform your physician before you take this medicine if you are diagnosed with a tumor in the lungs.
Breastfeeding: Consult your doctor Consult your physician for advice on taking this medicine if you are a breastfeeding mother.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.