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Azashine 300mg Tablet
Salt Composition: AZACITIDINE
- Manufacturer: HETERO HEALTHCARE LTD
- Pack Size: 14 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 300MG
- Prescription Required
- Storage: Store the tablets at an ideal temperature of 25°C, away from moisture and direct sunlight. Keep out of reach of children.
₹11250.00₹22500.00
Inclusive of all taxes
Product Introduction
Azashine 300mg Tablet is a pharmaceutical agent designed to treat severe blood disorders including Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia (AML). It is indicated for patients with these conditions who are not suitable candidates for stem cell transplantation. The active component, Azacitidine, works by targeting the synthesis of DNA and RNA in cancer cells, reducing their ability to replicate. This mechanism is important for managing conditions that significantly impair the production and function of blood cells, which can lead to severe health complications. Appropriate treatment of these conditions can improve survival outcomes and quality of life for affected patients. Understanding how this medication interacts with the body and other medications is important for optimising its therapeutic benefits and minimising potential risks.
Uses
Effective in managing symptoms and improving blood counts. Targets abnormal cell growth in the bone marrow. Helps in achieving remission of cancerous cells.
How it works
Azashine 300 mg tablet binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells. This mechanism is critical in reducing the proliferation of malignant cells and effectively managing blood-related cancers. Its action emphasizes its efficacy in conditions characterized by rapid cell growth, ensuring controlled disease management and extending patient survival.
How to Use
Azashine 300mg Tablet Dosages are meticulously tailored based on individual health conditions, body weight, and overall treatment objectives, ensuring that each patient feels confident in the precision and efficacy of their treatment. To maintain its effectiveness, the tablet should be swallowed whole with water and not altered (crushed, chewed, or broken).
Side Effects
Here are some frequently seen and serious side effects you need to be aware of: Common Nausea and vomiting are often experienced by many. Diarrhea is a frequent digestive system reaction. General fatigue is a widespread side effect. Headaches and dizziness are common neurological symptoms. Stomach pain and constipation are typical gastrointestinal issues. Rash and itching are common dermatological reactions. Serious Bruising or bleeding, indicating potential blood disorders. Abnormal liver function test results suggest liver issues. Swelling of facial areas, a sign of severe allergic reactions. Higher risk of catching infections due to a decreased white blood cell count. Shortness of breath, which may indicate respiratory problems. Anemia, which can lead to significant fatigue and weakness.
Expert Tips
Before administering this tablet, it is crucial to notify the doctor of any allergies, respiratory issues, or existing kidney, liver, or heart conditions the patient may have, as well as any other medications being taken, since they may exacerbate the patient's health issues. This medication should not be used if the patient is trying to conceive, is pregnant, or is breastfeeding due to its potentially harmful effects on the developing baby. This tablet should be taken strictly under medical supervision, with dosages tailored by the doctor according to the patientâs height, weight, and overall health condition.
References
- K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741, [Accessed on 5th Apr 2021] https://www.researchgate.net/publication/7094896_Transcriptional_repression_in_eukaryotes_Repressors_and_repression_mechanisms
- Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018 [Accessed on 3rd Apr 2021] https://bmchematol.biomedcentral.com/articles/10.1186/s12878-017-0094-8
- Dr.Reddyâs Laboratories, [Revised on 8th Nov 2018] [Accessed on 5th Apr 2021] https://www.drreddys.com/media/743001/ac-pm-english.pdf
Safety Advice
Pregnancy: unsafe Azashine 300 mg tablets should not be used during pregnancy. If you are pregnant or suspect you might be, please consult your doctor.
Lungs: Consult your doctor Before taking Azashine 300 mg tablets, inform your doctor if you have any respiratory issues.
Breastfeeding: unsafe If you are breastfeeding, seek advice from your doctor before using Azashine 300 mg tablets.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.