Azatend 100mg Injection

Azatend 100mg Injection is indicated for treating adults with Myelodysplastic syndrome (MDS) and Acute myeloid leukaemia (AML) who are ineligible for stem cell transplant. The active ingredient is azacitidine. In Myelodysplastic Syndrome, the bone marrow fails to produce healthy blood cells due to impaired function. Acute Myeloid Leukaemia is a bone marrow malignancy characterised by the release of incompletely formed blood cells into the bloodstream.

Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant Intermediate-2 and High-risk Myelodysplastic syndrome (MDS)

In MDS and AML, the development of tumor cells is caused by the process of transcriptional repression of various genes, which is due to hypermethylation of DNA. Transcriptional repression is a process where proteins bind directly or indirectly to DNA and control the activity of copying a specific gene or a set of genes. The active form of Azatend 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Take Azatend 100mg Injection only under the supervision of your physician. Your physician will decide the dose based on your height, weight, and general condition. Azatend 100mg Injection shall be given under the skin of your thigh, stomach, or upper arm.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Unexpected bleeding, with blood in stool and urine Fever Pneumonia, is characterized by chest pain or breathlessness. Allergic reaction with symptoms of swelling of lips, itching, or rashes. Seizures, loss of consciousness, severe headache, or bleeding in the brain Frequent urination with pain or burning sensation Common: Disturbances in the blood count (RBC, WBC, Platelets) Nausea, vomiting, diarrhea Constipation Tiredness Skin reactions like redness and pain at the site of injection Decreased appetite Dizziness Pain in extremities Joint pain Stomach pain Headache Sore nose and throat Rashes and bruising

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects in the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach, or upper arm.