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Barinat 1mg Tablet

Salt Composition: BARICITINIB

₹158.00₹196.88

Inclusive of all taxes

Categories: Hematology

Conditions: Others

Product Introduction

Barinat 1mg tablet contains baricitinib as its active component. It belongs to the class of Janus kinase (JAK) inhibitors. It is used primarily to treat certain autoimmune conditions, particularly rheumatoid arthritis, a chronic autoimmune disorder that primarily affects the joints. Treatment with this medication may improve quality of life and ability to perform daily activities. It can lead to reduction in pain, swelling, and stiffness associated with rheumatoid arthritis. It is approved for use in patients who have not responded adequately to conventional disease-modifying antirheumatic drugs (DMARDs) or other treatments. It helps reduce inflammation and manage symptoms associated with rheumatoid arthritis. During the COVID-19 pandemic, there was interest in using this medication as a potential treatment for severe cases of COVID-19.

Patients with known hypersensitivity or allergic reaction to baricitinib or any component of Barinat 1mg tablet should not use this medication. It should not be used in patients with active serious infections, including tuberculosis, bacterial, fungal, or viral infections. This medication can affect the immune system's response to vaccines; live vaccines are generally not recommended while taking this medication. The safety and efficacy of Barinat 1mg tablet have not been established in paediatric patients under 18 years, so it is not typically used in this age group. Older adults often have a higher likelihood of multiple medical conditions and concurrent medications, making consultation with a doctor necessary before taking this medication.

Uses

Barinat 1mg tablet is used in the following: Rheumatoid arthritis treatment Autoimmune condition management Combination therapy for rheumatoid arthritis Investigational use in COVID-19 Immunosuppressive effects

How it works

Barinat 1mg tablet is a Janus kinase (JAK) inhibitor, targeting JAK1 and JAK2 enzymes. These enzymes are integral to intracellular signaling pathways involved in immune responses and inflammation. By inhibiting JAK1 and JAK2, it interferes with transmitting signals that contribute to the activation of immune cells and the production of inflammatory molecules. This modulation of signaling pathways leads to a dampened immune response and reduced inflammation, effectively managing autoimmune conditions like rheumatoid arthritis.

How to Use

Barinat 1mg tablet is typically administered orally, which means it is taken by mouth as tablets. It is available as an oral tablet for easy ingestion. Your healthcare provider will determine the specific dosage and frequency of administration based on your medical condition and individual needs.

Side Effects

Barinat 1mg tablet causes some side effects like all medications, although not everyone will experience them. Serious Serious infections Blood clots Malignancies Gastrointestinal perforations Liver abnormalities Common Upper respiratory tract infections Headache Increased liver enzymes High blood pressure Changes in blood cell counts Elevated cholesterol levels

Expert Tips

Discuss your cardiovascular health with your healthcare provider before starting Barinat 1mg tablet. Monitor blood sugar levels closely and consult your healthcare provider if adjustments to diabetes management are needed. Gastrointestinal perforations, liver abnormalities, and possible gastrointestinal issues should be noted. Closely monitor liver enzymes, cholesterol, and blood pressure. Screen for hepatitis B before starting treatment. Vaccination schedules may need adjustment. Stomach and intestinal problems, surgery planning, cataracts, and drug allergies require attention. Use caution in individuals with a history of or risk factors for interstitial lung disease, as it may exacerbate this condition. Consider the risk of lymphoma and other malignancies might be increased with this medication. Protect your skin from sun exposure and report any skin changes to your healthcare provider. Regular eye check-ups are advisable.

References

  1. Eli Lilly and Company Limited, US Food and Drug Administration, [Revised on 5/2022] [Accessed on 29th Aug 2023], / https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/207924s006lbl.pdf
  2. Eli Lilly and Company Limited, Electronic Medicines Compendium (EMC), [Revised on 23rd Mar 2023] [Accessed on 29th Aug 2023], https://www.medicines.org.uk/emc/product/909/smpc#gref

Safety Advice

Pregnancy: Consult your doctor It is important to discuss your pregnancy status with your healthcare provider before starting Barinat 1mg tablet, as its safety in pregnancy is not well-established.

Lungs: Consult your doctor Barinat 1mg tablet can increase the risk of respiratory infections. If you have a history of lung issues, discuss the potential risks and benefits with your healthcare provider.

Breastfeeding: Consult your doctor The safety of Barinat 1mg tablet during breastfeeding is uncertain. It's recommended to consult a healthcare provider before using the medication while breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS