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Barinat 4mg Tablet
Salt Composition: BARICITINIB
- Manufacturer: NATCO PHARMA LTD
- Pack Size: 14 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 4MG
- Prescription Required
- Storage: Store at room temperature, between up to 20°C -25°C Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹335.00₹392.81
Inclusive of all taxes
Product Introduction
Barinat 4mg tablet contains baricitinib as its active component. It belongs to the class of Janus kinase (JAK) inhibitors. The medication is used primarily to treat certain autoimmune conditions, particularly rheumatoid arthritis, a chronic autoimmune disorder that primarily affects the joints. Treatment with this medication can enhance quality of life and ability to perform daily activities. It can lead to a reduction in pain, swelling, and stiffness associated with rheumatoid arthritis. The medication is approved for use in patients with rheumatoid arthritis who have not responded well to conventional disease-modifying antirheumatic drugs (DMARDs) or other treatments. It helps reduce inflammation and manage symptoms associated with rheumatoid arthritis. During the COVID-19 pandemic, there was some interest in using this medication as a potential treatment for severe cases of COVID-19.
Individuals with known hypersensitivity or allergic reaction to Barinat 4mg tablet or any of its components should not use this medication. It should not be used in patients with active serious infections, including tuberculosis, bacterial, fungal, or viral infections. This medication can affect the immune system's response to vaccines; live vaccines are generally not recommended while taking this medication. The safety and efficacy of Barinat 4mg tablet have not been established in paediatric patients under 18 years of age, so it is not typically used in this age group. Older adults often have a higher likelihood of multiple medical conditions and concurrent use of multiple medications; consultation with a doctor is necessary before taking this medication.
Uses
Barinat 4mg tablet is used in the following: Rheumatoid arthritis treatment Autoimmune condition management Combination therapy for rheumatoid arthritis Investigational use in COVID-19 Immunosuppressive effects
How it works
Barinat 4mg tablet is a Janus kinase (JAK) inhibitor, targeting JAK1 and JAK2 enzymes. These enzymes are integral to intracellular signaling pathways involved in immune responses and inflammation. By inhibiting JAK1 and JAK2, it interferes with transmitting signals that contribute to the activation of immune cells and the production of inflammatory molecules. This modulation of signaling pathways leads to a dampened immune response and reduced inflammation, effectively managing autoimmune conditions like rheumatoid arthritis.
How to Use
Barinat 4mg tablet is typically administered orally, which means it is taken by mouth as tablets. It is available as an oral tablet for easy ingestion. Your healthcare provider will determine the specific dosage and frequency of administration based on your medical condition and individual needs.
Side Effects
Barinat 4mg tablet causes some side effects like all medications, although not everyone will experience them. Serious Serious infections Blood clots Malignancies Gastrointestinal perforations Liver abnormalities Common Upper respiratory tract infections Headache Increased liver enzymes High blood pressure Changes in blood cell counts Elevated cholesterol levels
Expert Tips
Discuss your cardiovascular health with your healthcare provider before starting Barinat 4mg tablet. Monitor blood sugar levels closely and consult your healthcare provider if adjustments to diabetes management are needed. Gastrointestinal perforations, liver abnormalities, and possible gastrointestinal issues should be noted. Closely monitor liver enzymes, cholesterol, and blood pressure. Screen for hepatitis B before starting treatment. Vaccination schedules may need adjustment. Stomach and intestinal problems, surgery planning, cataracts, and drug allergies require attention. Use caution in individuals with a history of or risk factors for interstitial lung disease, as it may exacerbate this condition. Consider the risk of lymphoma and other malignancies might be increased with this medication. Protect your skin from sun exposure and report any skin changes to your healthcare provider. Regular eye check-ups are advisable.
References
- Eli Lilly and Company Limited, US Food and Drug Administration, [Revised on 5/2022] [Accessed on 29th Aug 2023], / https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/207924s006lbl.pdf
- Eli Lilly and Company Limited, Electronic Medicines Compendium (EMC), [Revised on 23rd Mar 2023] [Accessed on 29th Aug 2023], https://www.medicines.org.uk/emc/product/909/smpc#gref
Safety Advice
Pregnancy: Consult your doctor It is important to discuss your pregnancy status with your healthcare provider before starting Barinat 4mg tablet, as its safety in pregnancy is not well-established.
Lungs: Consult your doctor Barinat 4mg tablet can increase the risk of respiratory infections. If you have a history of lung issues, discuss the potential risks and benefits with your healthcare provider.
Breastfeeding: Consult your doctor The safety of Barinat 4mg tablet during breastfeeding is uncertain. It's recommended to consult a healthcare provider before using the medication while breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.