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Bdparib 200mg Tablet

Salt Composition: RUCAPARIB

₹33750.00₹42187.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Bdparib 200mg tablet contains the active ingredient rucaparib. It is an anti-cancer medicine that belongs to the class of medications called PARP (poly ADP-ribose polymerase) inhibitors. It is used to help maintain the response to other treatments for certain types of ovarian cancer, fallopian tube cancer (a tube that transports eggs released by the ovaries to the uterus), and primary peritoneal cancer (layer of tissue that lines the abdomen) that has recurred in adults who have previously completely responded or partially responded to other chemotherapy treatments. It is also used to treat certain types of cancer in patients with specific gene (BRCA) changes who have received treatment with at least two other chemotherapy treatments. It is also indicated as maintenance therapy immediately after chemotherapy which has caused the tumour to shrink. Do not take Bdparib 200mg tablet if you are allergic to Bdparib or any of the ingredients. This medication can cause low blood counts; hence your healthcare professional will advise you to take certain blood tests before and every month during the treatment. Inform your doctor if you have nausea, vomiting, diarrhoea, or abdominal pain during the treatment because this medicine may affect your stomach or bowels. Bdparib 200mg tablet should not be given to patients under 18 years of age. Notify your physician if you are pregnant, breastfeeding, suspecting, or planning for pregnancy during the treatment with this medicine. Patients with reproductive potential should use effective contraception during the treatment.

Uses

Ovarian cancer Fallopian tube cancer Primary peritoneal cancer Prostate cancer

How it works

Bdparib 200mg tablet is an inhibitor of poly Adenosine diphosphate-ribose polymerase enzymes, including PARP-1, PARP-2, and PARP-3, which play a role in DNA repair. It blocks an enzyme that repairs damaged DNA in the cancer cells, resulting in their death.

How to Use

It is an orally available prescription drug. Your doctor will decide the dose and duration of Bdparib 200mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Rash Constipation Decrease in appetite Diarrhea, indigestion Nausea, vomiting Changes in the blood count Shortness of breath Tiredness Serious Severe anemia Hypersensitivity reactions Sepsis (blood infection) Pneumonia

Expert Tips

You may get sunburn easily during treatment with Bdparib 200mg tablet. Keep out of direct sunlight and wear protective clothing that covers your head, arms, and legs. Use sunscreen and lip balm with a sun protection factor (SPF) after consulting your doctor. If you vomit after taking the medicine, do not take an extra dose. Take your next dose at the regular time. Do not stop taking this medicine without talking to your doctor. Your doctor may do lab tests to check the therapy's effectiveness or monitor the unwanted side effects.

References

  1. Rubraca 250mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [revised on 2022] [cited 2023 Apr 11]. Available from: https://www.medicines.org.uk/emc/product/10027/smpc
  2. HIGHLIGHTS OF PRESCRIBING INFORMATION - Rucaparib. [revised on 2018] [cited 2023 Apr 11]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/209115s003lbl.pdf
  3. Shirley M. Rucaparib: A Review in Ovarian Cancer. Targeted Oncology. [2019 Apr 1] [cited 2022 Oct 15];14(2):237–46. Available from: https://pubmed.ncbi.nlm.nih.gov/30830551/

Safety Advice

Pregnancy: unsafe Do not take Bdparib 200mg tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for 6 months after the last dose.

Lungs: Consult your doctor It is unknown whether Bdparib 200mg tablet is safe to be administer in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Bdparib 200mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS