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Benzace 40mg Tablet
Salt Composition: MEGESTROL
- Manufacturer: ADMAC LIFE SCIENCES
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 40MG
- Prescription Required
- Storage: Store below 25°C, protected from light and moisture.
₹157.00₹235.78
Inclusive of all taxes
Product Introduction
Benzace 40mg Tablet contains megestrol, a progestogen used in the treatment of hormone-dependent breast cancer. Megestrol is a synthetic form of the naturally occurring hormone progesterone.
The medication is also indicated for the management of unexplained weight loss, cachexia (muscle weakness) and anorexia (loss of appetite) in patients with compromised immune systems and cancer. Progestogens are employed in patients whose disease has advanced despite conventional anti-estrogen therapy. Your physician will assess oestrogen receptor (ER) status to confirm that your breast cancer expresses the oestrogen receptor.
Uses
Treatment of hormone-dependent cancer (endometrial cancer, breast cancer) Treatment of anorexia, cachexia or unexplained weight loss
How it works
Benzace 40mg Tablet exhibits anticancer properties by interacting with steroidal receptors. It suppresses steroid production by the adrenal glands and androgen secretion by the ovaries in postmenopausal women. It also prevents the breakdown of cytokines and stimulates appetite in chronic disease-induced anorexia and cachexia.
How to Use
Swallow the tablet whole with water. Your physician will decide the ideal dose for you, depending on your condition.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Swelling of the face, lips, tongue Skin rash Breathing difficulty Blood clot in the lungs Heart problems Common: Weight gain and increased appetite Hot flushes High BP High blood sugar levels Rounded face Constipation Swelling of vein Mood changes Hair loss Diarrhea Tiredness and weakness Impotence Passing wind Frequent urination Nausea, vomiting Fluid accumulation Pain
Expert Tips
Inform the doctor if the patient has any history of kidney, liver, or allergic reactions before starting this medication. Kidneys, liver, blood pressure, and blood glucose levels should be monitored while taking this medication. Avoid taking this medication while planning for pregnancy or during pregnancy, as it causes harmful effects on developing babies. This medication should not be stopped without proper advice from the doctor because it can worsen the situation. Inform the doctor immediately if any sign of swelling and pain in the limbs, shortness of breath, chest pain, severe headache, or changes in vision.
References
- Bausch and Lomb UK Ltd., Electronic Medicines Compendium (EMC), [Revised on Sep 2020] [Accessed on 17th Jul 2021], https://www.medicines.org.uk/emc/files/pil.11135.pdf
- alniche Life Sciences Pvt Ltd., [Revised on 2021] [Accessed on 19th Jul 2021], https://www.alniche.com/product/megahenz/
- Bines et al., Activity of megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial, Annals of Oncology, 2014, 25(4), 831-836, https://www.annalsofoncology.org/action/showPdf?pii=S0923-7534%2819%2936501-9
- G.G. Dark, A.R. Abdul Razak, Oncology, Davidsonâs Principles and Practice of Medicine, 22nd Edition, 2014, 259-282.
Safety Advice
Pregnancy: unsafe This medicine is unsafe to consume during pregnancy. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.
Lungs: Consult your doctor Inform your physician if you have any lung diseases before taking Benzace 40 mg tablet.
Breastfeeding: Consult your doctor Consult your physician before taking this tablet if you are a breastfeeding mother.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.