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Bevacirel 400mg Injection
Salt Composition: BEVACIZUMAB
- Manufacturer: RELIANCE LIFE SCIENCES PVT LTD
- Pack Size: 1 VIAL(s) OF 16ML
- Dosage Form: INJECTION
- Strength: 400MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store Bevacirel 400mg Injection at 2ËC to 8ËC. Do not freeze or shake. Protect from light. Keep out of reach of children.
₹11378.00₹68835.00
Inclusive of all taxes
Product Introduction
Bevacirel 400mg Injection is an anticancer medication containing Bevacizumab as the active ingredient. It works by blocking the growth of blood vessels that supply oxygen and nutrients to tumours, thereby slowing or stopping cancer progression. This injection is used in combination with other chemotherapy drugs to treat several types of cancers, including lung cancer, brain tumours, colorectal cancer, breast cancer, cervical cancer, kidney cancer, and ovarian cancers. The dosage for lung cancer and other cancers varies depending on the patient's weight, overall health, and treatment response. It is administered as an intravenous infusion under the supervision of an oncologist.
Patients undergoing treatment are advised to use effective birth control during therapy and for at least six months after the final dose, as the drug can affect fertility. Breastfeeding should also be avoided during treatment.
Bevacirel 400mg Injection may be prescribed in rare cases under specialist supervision to manage certain vision-threatening conditions caused by abnormal blood vessel growth. This medicine requires cold chain storage at recommended temperatures to maintain its stability and effectiveness.
Manufactured by Reliance Life Sciences, Bevacirel 400mg is available through verified online pharmacies ensuring safe handling and delivery. The price may differ based on location and hospital procurement. Doctors may also suggest a substitute such as Cizumab or other biosimilars. A comparison between Bevacirel 400mg and Cizumab 400mg often highlights similar efficacy since both contain the same active ingredient.
In certain cases, it is used for brain tumour management when combined with radiation or chemotherapy. Patients facing financial challenges may explore assistance programmes, which provide cost support through authorised distributors or oncology foundations.
Uses
Bevacirel 400mg usesin the following conditions: Glioblastoma multiforme (brain cancer) Persistent, recurrent, or metastatic breast cancer Metastatic cervical cancer Advanced kidney cancer Metastatic colorectal cancer Advanced non-small-cell lung cancer Liver Cancer- Hepatocellular carcinoma Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer
How it works
Bevacirel 400mg Injection is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers. It produces its action by selectively binding to the protein called vascular endothelial growth factor A (VEGF-A), present in the lining of blood and lymph vessels in the body. It interrupts the interaction of VEGF-A with its receptors. This further inhibits the formation of blood vessels that supply oxygen and nutrients to the tumor. As a result, it slows down the rate of progression of cancer.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Bevacirel 400mg side effects are Serious: Headache Vision changes Confusion Severe allergic reactions High Blood pressure Delayed wound healing following surgery Protein in urine Severe infections Blood clots in arteries and blood vessels of lungs Gut perforation Nosebleeds and bleeding risk Heart problems with an increase in heart rate Mouth sores, dryness Shortness of breath Common: Numbness in hands or feet Weakness and lack of energy Diarrhoea, nausea, vomiting, abdominal pain Constipation Loss of appetite Weight loss Changes in taste and speech Decrease in counts of white blood cells Fever Dry skin Back pain
References
- 1. Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 21/11/2022], https://www.medicines.org.uk/emc/files/pil.3885.pdf 2. G.G. Dark, A.R. Abdul Razak, Oncology, Davidson's Principles & Practice of Medicine, 22nd Edition, 2014, 259-282. 3. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936. 4. Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976. 5. Roche Group, U.S FDA, [Revised on Jan 2021][ Accessed on 21/11/2022], https://www.gene.com/download/pdf/avastin_prescribing.pdf 6. Roche Group,Bevacizumab Injection, Indication,[Revised on 2020] [Accessed on 21/11/2022] https://www.avastin.com/patient/mcrc.html
Safety Advice
Pregnancy: unsafe Inform your physician before starting your treatment with Bevacirel 400mg Injection in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.
Lungs: Consult your doctor Infor your doctor if you have any lung conditions before starting treatment with Bevacirel 400mg injection
Breastfeeding: unsafe It is recommended to avoid breastfeeding for a minimum of 6 months after your treatment with Bevacirel 400mg Injection as this medicine may interfere with the growth of your child.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.