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Bharglob 16.5% Injection 2ml

Salt Composition: HUMAN NORMAL IMMUNOGLOBULIN

₹904.00₹1004.98

Inclusive of all taxes

Categories: Others

Conditions: Immunoglobulins

Product Introduction

Bharglob 16.5% Injection 2ml is an immunostimulant drug classified as an immunoglobulin derivative, containing Human Normal Immunoglobulin as the active ingredient. It is indicated as replacement therapy for patients with primary immunodeficiency disorders (PIDs), in which the immune system cannot produce adequate antibodies to combat infections. The medication is also used to modulate the immune system in certain autoimmune and inflammatory conditions, helping to reduce excessive inflammation and suppress abnormal immune responses.

This drug is contraindicated in patients with known hypersensitivity or allergy to it or its components. Stop use and contact your doctor immediately if you develop a rash or skin symptoms. Patients with selective IgA deficiency face a risk of developing antibodies against IgA. In such cases, normal human immunoglobulin should be used with caution or avoided entirely. Inform your physician if you have a history of IgA deficiency.

Following administration of Bharglob 16.5% Injection 2ml, patients may experience a temporary decrease in white blood cell concentration, a condition termed neutropenia (low neutrophil count), which typically resolves spontaneously within a week. Normal human immunoglobulin administration may interfere with the efficacy of live attenuated vaccines. It is advisable to avoid live vaccines for a period following this drug's administration.

Overdose of Bharglob 16.5% Injection 2ml may result in fluid overload, particularly in patients with pre-existing heart failure or compromised renal function. Patients with such conditions require careful monitoring during infusion. Inform your doctor of any heart, thyroid, kidney, or liver disease. Your physician may prescribe a low dose and perform regular blood tests. Use of this medicine during pregnancy or breastfeeding should be discussed with your physician.

Uses

The Injection Bharglob uses include: Treat inflammatory disorders Primary immunodeficiency disease (PID)

How it works

Bharglob 16.5% Injection 2ml works by restoring the immunoglobulin G (IgG) antibodies. It directly binds to the Fc fragment-specific receptors and acts against inflammatory mediators. It induces cell death in B and T cells, eventually reducing inflammation and the severity of infections.

How to Use

Bharglob 16.5% Injection 2ml is usually administered through a vein (intravenously) by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Side Effects

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them. Serious Severe allergic reaction (rash, itching, swelling of lips, tongue, wheezing, difficulty breathing, low blood pressure with confusion, dizziness, fainting) Meningitis (inflammation of the brain) Respiratory failure Migraine High blood pressure Blood clot in lungs Rupturing of red blood cells Common Rash Itching Wheezing Difficulty in breathing Swelling of the eyelids Fever Confusion Dizziness Low BP

Expert Tips

If you have a current or past history of a kidney disorder, it is important to inform your physician. They will exercise caution and closely monitor your kidney function during treatment with Inj bharglob 16.5. Eat a well-balanced diet. You should avoid driving or handling machines if you feel dizzy or tired. Do not touch or rub your skin after injecting this medicine. Wear loose-fitting clothing to avoid discomfort.

References

  1. Biotest Pharma GmbH, Electronic medicines compendium (EMC), [ Revised on March 2020] [ Accessed on 30th June 2023], https://www.medicines.org.uk/emc/files/pil.576.pdf
  2. CSL Behring LLC, US Food and Drug Administration, [ Revised on Sept 2017] [ Accessed on 30th June 2023], https://www.fda.gov/files/vaccines%2C%20blood%20%26%20biologics/published/Package-Insert---Privigen.pdf
  3. Octapharma USA Inc., US Food & Drug Administration, [Revised on Mar 2022] [Accessed on 30th June 2023], https://www.fda.gov/media/70911/download
  4. Novaretti MC, Dinardo CL, Immunoglobulin: production, mechanisms of action and formulations, Rev Bras Hematol Hemoter, 2011, 33(5), 377-82, [Accessed on 30th June 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415776/pdf/rbhh-33-377.pdf

Safety Advice

Pregnancy: Consult your doctor Bharglob 16.5% Injection 2mls should be taken if it is necessary during pregnancy. Bharglob injection 16.5 in pregnancy should only be used under medical supervision. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment.

Lungs: Consult your doctor It is unknown whether Bharglob Injection is safe for patients with lung problems. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: Consult your doctor Bharglob 16.5% Injection 2mls should be taken if it is necessary during breastfeeding. Consult your doctor for more advice.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS