Bonitar 400mg Tablet

Bonitar 400mg Tablet contains the active ingredient bosutinib. It is a tyrosine kinase inhibitor indicated for adult patients with Philadelphia chromosome-positive (Ph-positive) Chronic Myeloid Leukaemia (CML) who are newly diagnosed or for whom prior CML treatments have failed, proved ineffective, or are unsuitable. Philadelphia chromosome-positive chronic myelogenous leukaemia is a blood cancer characterised by overproduction of a specific type of white blood cell called granulocytes.

Common side effects of Bonitar 400mg Tablet include low white blood cell count (leukopenia), headache, shortness of breath, joint pain, dizziness, cough, back pain, decreased appetite, respiratory tract infection, raised blood pressure, tinnitus, itching, acne, dehydration, taste change, photosensitivity, and fluid on lungs. Inform your doctor if any of these symptoms affect you or persist.

Inform your physician if you are allergic to Bonitar 400mg Tablet or any of its ingredients. Before taking this medication, report to your doctor if you have heart problems, bleeding problems, kidney or liver disorders, infection, or diarrhoea. This medicine is not recommended for children under 18 years of age. Limit time spent outdoors and use sunscreen when going outside, as this medicine can increase sensitivity to sun exposure and UV rays.

Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML).

Bonitar 400mg Tablet works by inhibiting the activity of an enzyme called Bcr-Abl kinase that promotes the growth and spread of blood cancer (Ph+ CML). This helps to slow or stop the growth and spread of cancer cells.

Take Bonitar 400mg Tablet in the dose and duration prescribed by your doctor. Take this medicine once a day with food. Swallow it whole and avoid breaking or crushing the tablet. Do not handle or touch the broken tablets.

Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them. Serious Blood disorders (bleeding, fever, bruising) Stomach problems (stomach pain, vomiting, diarrhea, constipation, nausea) Hepatitis B reactivation Severe skin reactions Liver problems (yellowing of white part of eyes and skin, tea-colored urine) Heart problems (loss of consciousness, irregular heartbeat) Common Low white blood cell count (leukopenia) Headache, dizziness Cough, shortness of breath Joint pain, back pain Decreased appetite Respiratory tract infection Increase in blood pressure Ringing in the ears (tinnitus) Itching, acne Dehydration Taste change Sensitivity to light Fluid on lungs

Women taking Bonitar 400mg Tablet are advised to use effective contraceptives like birth control during treatment and for one month (30 days) after the last dose. Check with your healthcare provider and inform them if you take any other medications, including over-the-counter and prescription medicines, vitamins, and herbal supplements. It is suggested to use sunscreen with a good sun protection factor (SPF) because you are sensitive to sun or UV rays while taking this medication. Do not eat or drink grapefruit-containing food products as this may increase the blood level in your body.