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Bonspri Injection

Salt Composition: OFATUMUMAB

₹60000.00₹67657.50

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Bonspri Injection contains the active ingredient ofatumumab, a monoclonal antibody. It is used to treat adult patients with relapsing forms of multiple sclerosis (RMS). Before starting treatment, inform your doctor if you have immune system disorders, cancer, severe infection, or are planning vaccination. If you have a current or past history of hepatitis B infection, notify your doctor prior to commencing this medication, as it may reactivate the hepatitis B virus. Effective contraception must be used during treatment and continued for up to six months after the final dose. Inform your doctor if you become pregnant while taking this medication or within six months of the last dose. Common side effects include upper respiratory tract infections, decreased immunoglobulin M protein levels in the blood, oral herpes, and pain, itching, redness, or swelling at the injection site.

Uses

Bonspri Injection is used to treat adult patients having relapsing forms of multiple sclerosis (RMS).

How it works

In multiple sclerosis, the B cells (white blood cell type) which are a part of the immune system, along with the immune system attacks the protective layer surrounding the nerve cells. Bonspri Injection produces its effect by targeting and attaching to CD20 on the B cells (white blood cells) surface and causes cell lysis and depletion. This in turn reduces the chances of multiple sclerosis relapse, relieves its symptoms and slows down the disease progression.

How to Use

Bonspri Injection is to be used as prescribed by your healthcare provider. Do not self administer.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Common Upper respiratory tract infections (sore throat and runny nose) Urinary tract infections Decrease in the level of immunoglobulin M protein in the blood Oral herpes Pain, redness, swelling and itching at injection site.

Expert Tips

If you have used Bonspri Injection while being pregnant, then consult your doctor for advice before getting your new born baby vaccinated. If you feel your multiple sclerosis condition is worsening (like weakness or vision changes), or if you experience any new unusual symptoms while using this medication, then inform your doctor immediately. Fever, headache, muscle pain, chills and fatigue are common injection reactions that might occur while using this medication.

References

  1. Novartis Pharmaceuticals UK Limited, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 20th August 2022], https://www.medicines.org.uk/emc/files/pil.12433.pdf
  2. Novartis Pharmaceuticals Corporation, U.S. Food and Drug Administration, [ Revised on August 2020], [ Accessed on 20th August 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/125326s070lbl.pdf

Safety Advice

Pregnancy: unsafe Bonspri Injection might be unsafe during pregnancy. If you are pregnant, think you might be pregnant or are planning to get pregnant then consult with your doctor before starting treatment with this medication. Effective contraception is to be followed while using this medication and must be used up to 6 months after the last dose. If you have used this medication while being pregnant, then consult your doctor for advice before getting your new born baby vaccinated.

Lungs: Consult your doctor In rare cases Bonspri injection might cause lung problems. It is advisable to inform your doctor if you have any lung diseases prior to the treatment.

Breastfeeding: unsafe Bonspri Injection might be unsafe during breastfeeding as this medication can pass into the breast milk. Consult your doctor regarding any breastfeeding concerns you have before starting treatment with this medication.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS