Borteshil 2mg Injection

Borteshil 2mg injection is a chemotherapy medication belonging to the class of proteasome inhibitors. The active ingredient is Bortezomib. It is indicated for treatment of multiple myeloma and mantle cell lymphoma. Multiple myeloma is a malignancy involving plasma cell progression in the bone marrow. Mantle cell lymphoma is a less common cancer affecting the lymph nodes. This medication is used concomitantly with other chemotherapy agents including pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone or thalidomide in patients with newly diagnosed disease who are ineligible for autologous blood stem cell transplantation. Common side effects associated with Borteshil 2mg injection include pneumonia, loss of appetite, sensitivity, tingling and burning sensation of the skin, nausea, vomiting, diarrhoea, mouth ulcers, constipation, muscle and bone pain, hair loss, fever, infections, itching, redness, dehydration and gastrointestinal disturbances. Inform your physician if these side effects are troublesome or persist. Inform your doctor if you are allergic to Borteshil 2mg injection or any of its ingredients. Do not use this medication if you have severe pulmonary or cardiac disease. Before beginning treatment, inform your physician if you have neuropathy (nerve dysfunction), cardiac disorders, severe pulmonary disease, pulmonary disorders, posterior reversible encephalopathy syndrome, gastrointestinal disorders, thrombocytopenia (low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities occurring as a complication during cancer treatment) or hepatic disorders. Inform your doctor of diabetes, as Borteshil 2mg injection may affect blood glucose levels.

Treatment of multiple myeloma and mantle cell lymphoma.

Borteshil 2mg injection works by exerting a toxic effect on cancer cells. It inhibits the 26S proteasome and blocks a major cell signaling pathway. This inhibition of the signaling pathway makes the cancer cells sensitive to chemotherapy. This medicine also enhances the build-up of a protein and minimizes cancer cell growth and multiplication.

Borteshil 2mg injection is administered intravenously in your vein or subcutaneously under the skin. This injection should be given by a qualified healthcare professional experienced in the use of cytotoxic medications.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Muscle cramps Confusion, visual disturbances, seizures, and headache Breathlessness Swelling of feet Changes in heartbeat High blood pressure Fainting and tiredness Cough and chest tightness Common: Pneumonia Loss of appetite Sensitivity, tingling and burning sensation of the skin Nausea, vomiting, and diarrhea Mouth ulcers Constipation Muscle and bone pain Hair loss Fever Reduction in blood cell count Reduced kidney function Shivering Infections Itching and redness Dehydration Stomach problems Difficulty sleeping, anxiety, mood swings, depressed mood

It is advised that both men and women must use an effective contraception method during treatment and three months afterward. Treatment with borteshil 2mg injection can commonly cause a decrease in the number of red and white blood cells and platelets in your blood. Therefore, you will have to take regular blood tests before and during your treatment with bortezomib to check your blood cell counts regularly. Pregnant women should not handle borteshil 2mg injection as it contains cytotoxic agents. Using gloves and protective clothing is recommended to prevent skin contact.