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Bortetrust 2mg Injection
Salt Composition: BORTEZOMIB
- Manufacturer: MANKIND PHARMACEUTICALS LIMITED
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 2MG
- Prescription Required
- Storage: Store unopened vials in the refrigerator (2 °C – 8 °C) and protect them from light. Keep this medicine out of sight and reach of children.
₹1557.00₹1945.73
Inclusive of all taxes
Product Introduction
Bortetrust 2mg Injection is a proteasome inhibitor containing bortezomib. It is prescribed for the treatment of multiple myeloma and mantle cell lymphoma. This medicine is used alongside other chemotherapy agents such as pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone, or thalidomide, particularly in patients with previously untreated disease who are ineligible for blood stem cell transplantation. Dosage is individualised by the treating physician according to patient condition. The manufacturer maintains quality and safety standards. Patients may review alternative bortezomib 2mg formulations available in India and consider substitutes. Cost per vial and overall expense are factors in treatment planning. Patient experiences with Bortetrust 2mg Injection regarding its efficacy in cancer treatment are documented in clinical reviews.
Uses
Bortetrust 2mg uses are Treatment of multiple myeloma and mantle cell lymphoma.
How it works
Bortetrust 2mg Injection Injection works by exerting a toxic effect on cancer cells. It inhibits the 26S proteasome and blocks a major cell signaling pathway. This inhibition of the signaling pathway makes the cancer cells sensitive to chemotherapy. This medicine also enhances the build-up of a protein and minimizes cancer cell growth and multiplication.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Bortetrust 2mg side effects are Serious Muscle cramps Confusion, visual disturbances, seizures, and headache Breathlessness Swelling of feet Changes in heartbeat High blood pressure Fainting and tiredness Cough and chest tightness Common Pneumonia Loss of appetite Sensitivity, tingling and burning sensation of the skin Nausea, vomiting, and diarrhea Mouth ulcers Constipation Muscle and bone pain Hair loss Fever Reduction in blood cell count Reduced kidney function Shivering Infections Itching and redness Dehydration Stomach problems Difficulty sleeping, anxiety, mood swings, depressed mood
Expert Tips
Both men and women must use an effective contraception method during treatment and for three months afterward. Bortetrust 2mg Injection may cause a decrease in red blood cells, white blood cells, and platelets. Regular blood tests are required before and during treatment to monitor blood cell counts. Pregnant women should not handle this injection, as it contains cytotoxic agents. Gloves and protective clothing should be used to prevent skin contact with the medicine.
References
- STADA, Electronic Medicines Compendium (EMC), [Revised on Nov 2021] [Accessed on 30 Nov 2022], https://www.medicines.org.uk/emc/files/pil.10201.pdf
- Takeda Pharmaceuticals U.S.A., Inc., [Revised on Aug 2022] [Accessed on 30 Nov 2022], https://www.velcade.com/files/pdfs/VELCADE_PRESCRIBING_INFORMATION.pdf
- Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
- H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidsonâs Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056
Safety Advice
Pregnancy: unsafe Bortetrust 2mg Injection is unsafe to use during pregnancy unless clearly necessary. Both women of childbearing potential and men must use an effective contraception method during and three months after treatment.
Lungs: Consult your doctor It is unknown whether Bortetrust 2mg Injection can be given to lung failure patients. Please consult your physician if you have any lung diseases.
Breastfeeding: unsafe Bortetrust 2mg Injection is unsafe to use during breastfeeding. Please discuss with your physician when it is safe to restart breastfeeding after this treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.