Bucelon 2mg Tablet

Bucelon 2 mg tablet is an antineoplastic chemotherapy agent belonging to the alkylating agent class, specifically an alkyl sulfonate. It is indicated for treating blood cancers, including chronic myelogenous leukemia, a type of cancer that causes increased white blood cells. It is also given as a preparative treatment to condition the bone marrow to receive healthy blood-forming cells (stem cells) from a donor, replacing stem cells destroyed by radiation or high-dose chemotherapy.

Chronic myelogenous leukemia is an uncommon malignancy affecting bone marrow, the soft, spongy tissue that produces blood cells. The disease causes elevated white blood cell count.

Common side effects of Bucelon 2 mg tablets include decreased white blood cells, dizziness, shortness of breath, oral inflammation, nausea, diarrhoea, difficulty sleeping, and fever.

Maintain adequate fluid intake while taking this medicine. Bucelon 2 mg can cause severe suppression of bone marrow activity. If you are taking other prescribed or non-prescribed medications that decrease blood cell count, discuss with your healthcare professional before continuing these medications. Busulfan tablets affect immune system function. Patients may develop infections more readily, including serious or fatal infections. Contact your doctor if you experience fever, chills, cough, oral ulceration, or unusual bleeding or bruising.

Hematopoietic progenitor cell transplantation Chronic myelogenous leukaemia Polycythaemia vera (type of cancer that causes increase in red blood cells) Thrombocythemia (increased number of platelets in the blood) Myelofibrosis (type of blood cancer where scar tissues are formed in bone marrow) Hemoglobinopathies (a genetic disorder that produces abnormal haemoglobin)

Bucelon works by interfering with the DNA replication process, which is necessary for the cells to divide. It stops tumor growth by inhibiting cell division. They cause cytotoxicity by reversibly binding to nucleophilic groups on different cell components. Alkylation of DNA is most likely the crucial cytotoxic reaction that kills tumor cells. It damages the DNA and RNA of the cancer cells by stopping their growth and multiplication. They are combined with other medications to treat various lymphatic and solid cancers.

Your physician will decide the dose and duration of this therapy. The dose of Busulfan depends on your blood cancer. Swallow the tablets with plenty of water. Do not break, crush or chew them. You can take busulfan tablets before or after meals. Don't stop the medication until or unless your doctor advises. If you missed the dose, do not take double the doses. Inform your physician about your missed dose.

Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them. Severe Myelosuppression (decreased bone marrow activity) Common side effects Thalassaemia Hair loss Patches of dark skin Blood in urine Decrease in the number of blood cells and platelets Nausea and vomiting Jaundice Infertility and sterility Pneumonia syndrome

Inform the doctor if the patient has taken radiotherapy priorly to the treatment. If you have other medical conditions like heart disease, lung, kidney, or liver problems. Tell your doctor if you have gout symptoms (pain and swollen joints caused by uric acid crystals).