HomeProducts › Oncology › Buselin 7mg Injection

Buselin 7mg Injection

Salt Composition: BUSERELIN

₹2866.00₹3582.91

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Buselin 7 mg Injection contains Buserelin, a gonadotropin-releasing hormone (GnRH) analogue used to treat advanced prostate cancer, endometriosis, and as supportive therapy during ovulation induction. It may also be used as an adjunct treatment in certain pregnancy-related conditions.

Patients should immediately report symptoms such as abdominal pain, swelling, nausea, rapid weight gain, breathing difficulties, diarrhoea, or reduced urination, as these may indicate Ovarian Hyperstimulation Syndrome (OHSS), a serious adverse effect. The medicine may affect blood pressure and blood sugar control, making regular monitoring important, especially in patients with hypertension or diabetes.

Buselin may cause changes in liver function, blood lipid levels, bilirubin levels, and blood cell counts. Patients should inform their doctor about all medications, including over-the-counter and herbal products, to avoid potential drug interactions.

This medicine should not be used during pregnancy because it can harm the unborn baby. Effective contraception is recommended during treatment and for at least two weeks after the final dose. Breastfeeding should be avoided while receiving this medicine. Due to the presence of benzyl alcohol, it must not be administered to premature infants, newborns, or children under 3 years of age.

Some patients may experience dizziness, drowsiness, or blurred vision. If these effects occur, driving or operating machinery should be avoided.

Uses

Advanced prostatic carcinoma Treatment of endometriosis Adjunctive use in ovulation induction

How it works

It works by reducing the production of certain hormones in the body. This drug specifically gets binding to and stimulating GnRH receptors in the pituitary gland, which is located at the base of the brain. This leads to a transient increase in the production and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. However, with continued use, this injection suppresses the production of LH and FSH, leading to a decrease in the production of testosterone in men and estrogen in women.

How to Use

The medicine will be administered to you by a healthcare professional in a hospital setting. It is usually administered as an injection under the skin (subcutaneously) or as a nasal spray. The dose, route of administration, and frequency will be decided by your doctor based on your disease condition and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Allergic reactions like difficulty swallowing, rashes and swelling Diarrhea Pain and stomach problems Breathlessness Weight gain Low urination Sickness High BP Unusual bruising Severe headache and eyesight problems Infections Common Menopause-like symptoms Increased sweating, dry vagina, hot flushes Shoulder pain and stiffness Constipation or diarrhea Low glucose tolerance Mood changes, depression, anxiety Tinnitus Heart palpitations Hair loss Vaginal discharge Changes in liver enzymes

Expert Tips

It is recommended to quit smoking or limit tobacco use while taking this medication. Smoking may also worsen some of the side effects of this injection, such as the risk of cardiovascular disease. Avoid drinking grapefruit juice with this medicine as it may increase the levels of buserelin in the body, which can develop the risk of side effects. Buselin 7mg Injection may cause dizziness, drowsiness, or blurred vision, so it is important to avoid driving. If you miss a dose of this injection and it is close to the time for your next scheduled dose, you should skip the missed dose and continue with your regular dosing schedule.

References

  1. Neon Healthcare Ltd., Electronic Medicines Compendium (EMC), [Revised on Oct 2020] [Accessed on 11th April 2023], https://www.medicines.org.uk/emc/files/pil.11243.pdf
  2. Sanofi-Aventis Canada Inc, [Revised on Aug 2010], https://www.oncozine.com/wp-content/uploads/2017/07/Suprefact%C2%AE-buserelin-acetate.pdf [Accessed on 11th April 2023]
  3. Suprefact® 1 mg/ML solution for injection - hpra.ie. Available at: https://www.hpra.ie/img/uploaded/swedocuments/2160255.PA0540_074_001.718e6dbb-66a2-4c24-a718-2253b059c0d3.000001529108_Suprefact%C2%AE%201%20mgml.150821.pdf [Accessed on 11th April 2023].
  4. M.W.J. Strachan, J. Newell-Price, Endocrine disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 2014, 733-796.
  5. Roger K. Long, Hakan Cakmak, Hypothalamic & Pituitary Hormones, Lange's Basic & Clinical Pharmacology, 14th Edition, 2018, 667-686.

Safety Advice

Pregnancy: unsafe Buselin 7mg Injection is unsafe for pregnant women as it may harm the unborn baby.

Lungs: Consult your doctor It is unknown whether Buselin 7mg Injection can be used for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Buselin 7mg Injection is not recommended in breastfeeding women as it may pass into the breast milk.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS