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Buvalor 20mcg Patch

Salt Composition: BUPRENORPHINE TRANSDERMAL PATCH

₹3949.00₹4936.88

Inclusive of all taxes

Categories: Others

Conditions: Others

Product Introduction

Buvalor 20mcg patch contains buprenorphine as its active component in transdermal patch form. It is used to manage moderate to severe chronic pain and as part of opioid dependence treatment. The patch delivers buprenorphine, a partial opioid agonist, continuously through the skin into the bloodstream over time. This sustained delivery maintains steady blood levels of the medication, reducing the risk of misuse or diversion. The transdermal delivery system bypasses the gastrointestinal tract, which lowers the likelihood of common opioid-related side effects such as nausea and vomiting. The controlled release of buprenorphine may also result in a reduced incidence of certain other side effects. The patch format simplifies treatment and can improve adherence, as it eliminates the need for frequent dosing and reduces the likelihood of missed doses. This is particularly beneficial for patients with complex medication regimens or those who have difficulty swallowing tablets.

Use of this patch is contraindicated in patients with known hypersensitivity or allergy to buprenorphine or any patch components. The patch should be used with caution in patients with respiratory conditions such as chronic obstructive pulmonary disease (COPD), as it can affect respiratory function. This medication can potentially cause or worsen paralytic ileus, a condition characterised by impaired bowel motility, and should be used cautiously in patients at risk for bowel obstruction. Compared to immediate-release oral opioids, the patch has a slower onset of action, meaning pain relief may take time to achieve. Additionally, the effects may persist even after the patch is removed, which may be disadvantageous in the event of adverse reactions.

Uses

Chronic Pain

How it works

The Buvalor 20mcg patch provides a therapeutic effect by delivering a continuous and controlled release of buprenorphine into the bloodstream. As a partial opioid agonist, this medication binds to opioid receptors in the brain, producing analgesic (pain-relieving) effects for individuals with chronic pain and reducing withdrawal symptoms and cravings in those undergoing opioid dependence treatment.

How to Use

To use the Buvalor 20mcg patch, clean and dry the desired application site on the upper arm, chest, back, or side. Avoid areas with broken or irritated skin. Open the patch package and remove the protective liner, being careful not to touch the adhesive. Apply the patch firmly to the skin, ensuring good contact. Press down on the patch for about 30 seconds to secure it in place. Change the patch as directed by your healthcare provider, typically every 7 days.

Side Effects

Buvalor 20mcg patch causes some side effects like all medications, although not everyone will experience them. Serious: Difficulty breathing or shortness of breath Severe drowsiness or sedation Slowed or irregular heartbeat Allergic reactions, such as rash, hives, or swelling of the face, lips, or throat Mental or mood changes Signs of liver problems (yellow skin or eyes, dark urine, or persistent abdominal pain) Common: Nausea and vomiting Constipation Drowsiness or sedation Headache Sweating Skin reactions at the patch application site, such as itching, redness, or irritation

Expert Tips

Before using the Buvalor 20mcg patch, several precautions should be considered. Inform your healthcare provider about any allergies, medical conditions, or medications you are taking, as they may interact with buprenorphine. Caution is advised in individuals with respiratory disorders, liver or kidney problems, or a history of substance abuse. The patch should be applied to intact skin only and avoided on areas with rashes, burns, or wounds. Pregnant and breastfeeding women should consult a doctor before using it. Regular monitoring of vital signs, respiratory function, and liver function is recommended during treatment. It is important to avoid abrupt discontinuation of the patch without medical guidance, as it may result in withdrawal symptoms. The patch should be used cautiously in the elderly, as they may be more susceptible to the medication's effects. Additionally, special attention should be given to individuals with a history of mental health disorders or seizures.

References

  1. Lonza Biologics Tuas Pte Ltd, European Medicines Agency, [Revised on: 4/14/2020] [Accessed on 19th June 2023], https://www.ema.europa.eu/en/documents/product-information/reblozyl-epar-product-information_en.pdf
  2. Amneal Pharmaceuticals, LLC, US Food and Drug Administration, [Revised on 2017] [Accessed on 19th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2020/211586Orig1s000ltr.pdf

Safety Advice

Pregnancy: Consult your doctor If you are pregnant or planning to become pregnant, it is crucial to inform your healthcare provider. They can evaluate your circumstances, weigh the potential risks and benefits, and provide guidance specific to your situation.

Lungs: unsafe Buprenorphine, like other opioids, can cause respiratory depression and a decrease in breathing rate and depth. In individuals with pre-existing lung conditions, such as chronic obstructive pulmonary disease (COPD) or asthma, the risk of respiratory depression may be heightened.

Breastfeeding: Consult your doctor When it comes to the safety of using the Buvalor 20mcg patch while breastfeeding, it is important to consult with a healthcare professional.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS