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Calcispray Nasal Spray

Salt Composition: CALCITONIN

₹1717.00₹2172.10

Inclusive of all taxes

Categories: Orthopaedics

Conditions: Osteoporosis

Product Introduction

Calcispray Nasal Spray contains calcitonin as its active component. Calcitonin is a hormone that regulates calcium in the body. The thyroid gland produces it naturally, and it functions by lowering blood calcium levels through inhibition of calcium release from bones and increased calcium excretion via the kidneys. Synthetic calcitonin is used medicinally to manage specific conditions.

This medication is indicated for postmenopausal osteoporosis, Paget's disease of bone, and hypercalcaemia, and it prevents bone loss in patients with fractures. It strengthens bone tissue and reduces the risk of further deterioration. Calcispray Nasal Spray may reduce bone pain in patients with cancer that has metastasised to bone.

Do not use this medication in patients with known hypersensitivity or allergy to calcitonin or any component of the formulation. Allergic reactions may manifest as skin rash, itching, swelling, or difficulty breathing.

An alternative nasal spray formulation available in India is Calcitriol Nasal Spray. Because this medication lowers blood calcium levels, it should not be administered to patients with hypocalcaemia. Patients with impaired renal function may require dosage adjustments, as the kidneys eliminate this medication. Close monitoring is necessary to prevent potential accumulation.

Calcispray Nasal Spray may cause gastrointestinal side effects including nausea, vomiting, or diarrhoea.

Uses

Calcispray Nasal Spray uses to treat the following: Hypercalcemia Paget’s disease Postmenopausal osteoporosis Prevention of fracture.

How it works

The therapeutic effect of Calcispray Nasal Spray lies in its ability to regulate calcium levels in the body. As a hormone medication, this medication helps to reduce bone resorption and inhibits the release of calcium from bones, leading to decreased blood calcium levels. This effect is particularly beneficial in treating conditions such as osteoporosis, where it can slow down bone loss and potentially reduce the risk of fractures. This medicine also finds application in managing Paget's disease of bone, where it helps control abnormal bone remodelling and alleviates associated symptoms. Moreover, in emergency cases of hypercalcemia, this medication rapidly lowers blood calcium levels, relieving severe symptoms and preventing complications.

Side Effects

Calcispray Nasal Spray side effects like all other medications, although not everyone will experience them. Serious side effects of Calcispray Nasal Spray are: Allergic reactions Hypocalcemia (lower blood calcium levels) Respiratory issues Gastrointestinal bleeding Common side effects of Calcispray Nasal Spray are: Nausea Vomiting Diarrhea Headache Flushing of the face or skin Injection site reactions (for injectable formulations) Nasal irritation or dryness (for nasal spray)

References

  1. Novartis Pharmaceuticals Corporation, FDA (Food and Drug Safety Administartion) [Revised on 2011] [Accessed on 21st July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/017808s034lbl.pdf
  2. Essential Pharma (M) Limited, Health Products Regulatory Authority, [Revised on Sep 2020] [Accessed on 21st July 2023], https://www.hpra.ie/img/uploaded/swedocuments/Licence_PA22644-004-001_13112020161254.pdf
  3. K D Tripathi, Hormones and Drugs affecting calcium balance, Essentials of Medical Pharmacology, 8th Edition, 2019, 360-372.
  4. Thomas D. Nolin and Peter A. Friedman, Agents Affecting Mineral Ion Homeostasis and Bone Turnover, Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 13th Edition, 2018, 887-906.

Safety Advice

Pregnancy: Consult your doctor The safety of Calcispray Nasal Spray use during pregnancy has not been extensively studied, and its use in pregnant individuals should generally be avoided, and healthcare provider consultation is required.

Lungs: Consult your doctor Patients with lung infections or other respiratory conditions should consult their healthcare providers to ensure the appropriate use of Calcispray Nasal Spray or any other medication.

Breastfeeding: Consult your doctor The safety of using Calcispray Nasal Spray during breastfeeding has not been well-established, and it is generally recommended to avoid its use while breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS