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Calmac 50mg Tablet

Salt Composition: BICALUTAMIDE

₹388.00₹484.95

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Calmac 50mg Tablet contains the active ingredient Bicalutamide. It is indicated for treatment of advanced prostate cancer. It is classified as a non-steroidal anti-androgen. It is prescribed in combination with a Luteinizing Hormone-Releasing Hormone (LHRH) analog or following surgical castration. Calmac 50mg Tablet may be taken with or without food but should be taken at the same time each day. Dosage is individualised based on patient condition and should be taken as directed by your doctor. Do not exceed the prescribed dose, as this may cause serious adverse effects. This medication must be continued even when the patient feels well. It forms part of androgen deprivation therapy, which may be combined with radiation and surgical intervention in high-risk patients. Androgen deprivation therapy substantially reduces testosterone levels. Since prostate cancer is androgen-sensitive, this approach targets both the source and effects of androgen. Contact your doctor immediately if you develop blood in urine or severe allergic reactions during treatment.

Uses

Treatment of advanced prostate cancer

How it works

Calmac 50mg Tablet binds to the cytosol androgen receptors and blocks the effect of the androgen hormone. It interrupts the interaction of androgen receptors to hormones testosterone and dihydrotestosterone. This, in turn, blocks the growth of cancer cells in the prostate gland.

How to Use

Consume the tablet at the same time each day, with or without food.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Severe allergic reactions such as rashes, swelling, wheezing, etc Depression Heart problems Changes in liver enzymes Blood in urine Common: Body Pain Constipation Infection Nausea Peripheral edema Breathlessness Enlargement of breasts Anaemia Dizziness Weakness, swelling and breast tenderness Weight gain Indigestion Hair loss Low appetite Low sex drive Blood glucose problem

Expert Tips

This medication should be taken as prescribed by the doctor. This medication has to be taken with or without food but it should be taken at a fixed time daily. Inform the doctor about any allergic reactions, kidney, liver, diabetes, blood pressure and other medications taken for different medical conditions before starting this medication. Avoid driving and handling heavy machineries after taking this medication as it causes dizziness and individuals can lack consciousness and alertness. Blood count, blood pressure, liver, kidneys, blood glucose levels should be monitored regularly while using this medication.

References

  1. 1. AstraZeneca Pharmaceuticals, U.S. Food & Drug Administration, [Revised on Oct 2017] [Accessed on 15th June 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020498s028lbl.pdf 2. AstraZeneca, Electronic Medicines Compendium (EMC), [Revised on Apr 2020] [Accessed on 6th Dec 2021], https://www.medicines.org.uk/emc/files/pil.5491.pdf 3. Marina D. Kaymakcalan and Christy S. Harris, Prostate Cancer, Applied Therapeutics, The Clinical Use Of Drugs, 11th Edition, 2018, 2083-2100.

Safety Advice

Pregnancy: unsafe Calmac 50mg Tablet is not indicated to be used during pregnancy.

Lungs: Consult your doctor Talk to your doctor if you have any lung conditions before starting treatment with Calmac 50mg Tablet.

Breastfeeding: unsafe Calmac 50mg Tablet is not indicated to be used in breastfeeding women. Inform your doctor if you are breastfeeding before starting treatment with this medication.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS