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Campto 40mg Injection
Salt Composition: IRINOTECAN
- Manufacturer: PFIZER LTD
- Pack Size: 1 VIAL(s) OF 2ML
- Dosage Form: INJECTION
- Strength: 40MG
- Prescription Required
- Storage: Do not freeze. Store protected from light at a temperature not exceeding 25°C. Keep this medicine away from the sight and reach of children.
₹1620.00₹2025.94
Inclusive of all taxes
Product Introduction
Campto 40 mg Injection is an anti-cancer medicine belonging to the class of cytostatics. The active ingredient is Irinotecan hydrochloride trihydrate. It is indicated for advanced colon cancer and rectal cancer in adults. It may be prescribed as monotherapy or in combination with other chemotherapeutic agents. Colorectal cancer occurs predominantly in age groups above 50 and is influenced by genetic and environmental factors. Myelosuppression (bone marrow suppression resulting in decreased levels of red blood cells, white blood cells, and platelets) and diarrhoea are the most common adverse effects. Other common side effects include nausea, vomiting, abdominal pain, constipation, anaemia, pain, fatigue, fever, infections including sepsis, elevated bilirubin levels, alopecia, and weight loss. Inform your doctor if these side effects occur or persist. Notify your physician if you have an allergy to Campto 40 mg Injection or any of its ingredients. Before commencing treatment, disclose to your physician any history of liver disease or jaundice, kidney problems, cardiac disease, asthma, hypertension, hypercholesterolaemia, or severe diarrhoea. Report to your healthcare provider if you currently smoke or have previously received radiation therapy. Inform your healthcare provider of all medicines, herbal products, and supplements you are taking. Effective contraception by both males and females during treatment is essential to prevent pregnancy. Your physician will conduct blood tests before and during treatment to monitor the effects of the medication on blood counts and blood chemistry.
Uses
Treatment of metastatic cancer of the colon and rectum (large intestine).
How it works
Irinotecan hydrochloride trihydrate works by converting its active metabolite with the help of liver enzymes and inhibits the Topoisomerase I enzyme. This causes damage to the DNA synthesis and its replication, thus preventing the cancer cells from growing and spreading.
How to Use
Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. The dose depends on your age, size, and medical condition.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Early and late diarrhea Allergic reactions Kidney impairment Lung problems Low levels of RBC, WBC, and platelets in the blood Common: Nausea, vomiting, abdominal pain Constipation Diarrhea Anemia Pain Fatigue Fever, infections including sepsis Abnormal bilirubin levels Hair loss Weight loss
Expert Tips
Diarrhea is the first sign of Campto 40mg Injection. It may be serious if diarrhea starts more than 24 hours after administration of this medication. It should be treated immediately and kept under close supervision. If left untreated, it could lead to dehydration and serious chemical imbalances, which can be life-threatening. Try to avoid laxatives and stool softeners while taking this medicine. Drink large amounts of water and rehydration fluids immediately. Take antidiarrheal treatment like loperamide.
References
- Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 24 Nov 2022], https://www.medicines.org.uk/emc/files/pil.7318.pdf
- Pharmacia & Upjohn Co, US Food & Drug Administration, [Revised on Dec 2014] [Accessed on 24 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020571s048lbl.pdf
- I.D. Penman, C.W. Lees, Alimentary Tract and Pancreatic Disease, Davidsonâs Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.
- Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
Safety Advice
Pregnancy: unsafe Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. The dose depends on your age, size, and medical condition.
Lungs: Consult your doctor It is unknown whether it is safe to administer Campto 40mg Injection in patients with lung disorders. Please consult your doctor for more advice.
Breastfeeding: unsafe It is unsafe to use during breastfeeding as Campto 40mg Injection, and its metabolites are found in human milk. It must be discontinued for the duration of therapy. Consult your doctor for advice.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.