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Carmendan Injection
Salt Composition: LEVOSIMENDAN
- Manufacturer: RMPL PHARMA LLP
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 12.5MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store in refrigerator at (2°C-8°C) Do not freeze Do not dispose of the medication in wastewater or household waste. Always return to the pharmacy when you no longer require the medication.
₹747.00₹930.00
Inclusive of all taxes
Product Introduction
Carmendan Injection contains the active ingredient levosimendan and is classified as an inotropic agent. It is indicated for short-term management of acutely decompensated severe chronic heart failure (ADHF), characterised by sudden or gradual worsening of heart failure symptoms. This medication is used when standard treatments have provided insufficient relief and patients continue to experience dyspnoea or require fluid removal.
Do not use this medication if you are under 18 years of age or if you have known hypersensitivity to levosimendan or its components. Inform your healthcare provider if you have severe chronic kidney disease, severe chronic liver disease, or any specific cardiac condition, as use should be avoided in these situations. Before initiating this medication, inform your doctor if you have severe hypotension, anaemia, significant hypovolaemia, hypokalaemia, or tachycardia. Provide your healthcare provider with a complete medical history and a comprehensive list of all current medications prior to starting treatment.
Uses
Short-term management of acute decompensated heart failure (ADHF)
How it works
Carmendan injection exhibits its inotropic and vasodilatory action by sensitizing calcium channels, resulting in increased cardiac output without increasing the oxygen demand of the heart. It also lessens the congestion in your lungs, making it easier for blood and oxygen to go through your body, thereby relieving the shortness of breath due to severe heart failure.
How to Use
Carmendan injection is given only in a hospital setup by a healthcare provider. It is infused directly into your veins by your physician. Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Common Headache Abnormally fast heartbeat Drop in blood pressure A low amount of potassium in your blood Insomnia Dizziness Abnormally fast heartbeats (atrial fibrillation) Oxygen insufficiency Nausea Constipation Diarrhea Vomiting Low blood counts (anemia)
Expert Tips
Carmendan injection is strictly meant for in-hospital use and should be administered by your healthcare provider. Throughout your carmendan Injection treatment, your doctor will closely monitor your heart rate, blood pressure, and electrocardiogram (ECG) to measure how you are responding to the treatment. After you have finished the medication, your doctor will continue monitoring you for about 4-5 days and may adjust your dose when necessary. It is crucial to stick to your regular follow-up appointments to minimize the risk of side effects. For elderly patients, there are no dose adjustments done, but they require close monitoring. Carmendan injection can cause a drop in potassium levels, so your doctor might prescribe potassium supplements to prevent this. Also, consider incorporating iron-rich foods into your diet, as this medication can lead to anemia. Remember to schedule a complete cholesterol screening (lipid profile test) at least once a year to keep track of your heart health. Additionally, keep an eye on your blood pressure, heart rate, and electrolyte levels. Always consult your doctor if you have any concerns before starting this medication. If you experience any side effects during or after treatment, be sure to inform your healthcare provider promptly.
References
- As Kalceks, Health Products Regulatory Authority (HPRA), [Revised on Feb 2022], [Accessed on 21st Sept 2023], https://www.hpra.ie/img/uploaded/swedocuments/f255c6f4-40a8-4c0f-b034-e20069403900.pdf
- Orion Pharma, Sweden Medical Products Agency (MPA), [Revised on Jun 2010], [Accessed on 21st Sep 2023], https://www.simdax.com/siteassets/simdax-spc.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Cardiovascular drugs, 8th edition, 2019, 568
- Bertram G. Katzung, Drugs Used in Heart Failure, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 212-227.
Safety Advice
Pregnancy: Consult your doctor It is unknown whether carmendan injection is safe during pregnancy. Therefore, it is given when the benefit for the mother outweighs the risk to the fetus. Tell your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant before taking this medication.
Lungs: Consult your doctor It is unknown whether carmendan injection is safe for persons suffering from lung disease. Inform your doctor if you have any lung disease before starting the treatment.
Breastfeeding: unsafe There are indications that carmendan injection passes into human breast milk. Hence, you should not breastfeed while given this medicine to avoid potential cardiovascular side effects on your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.