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Cefglobe S Injection

Salt Composition: CEFOPERAZONE,SULBACTAM

₹81.00₹101.25

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Cefglobe S Injection contains cefoperazone and sulbactam. Cefoperazone is a third-generation cephalosporin antibiotic. Sulbactam is a beta-lactamase inhibitor. Together, these agents are effective against a wide range of bacteria and are used to treat serious infections including urinary tract infections, respiratory tract infections, intra-abdominal infections, septicaemia, meningitis, skin infections, bone infections, and endometritis.

This medication is contraindicated in individuals with known hypersensitivity or allergy to cefoperazone, sulbactam, or any component of the formulation. Inform your physician if you are allergic to any antibiotic group.

Consumption of alcohol (including alcoholic beverages, medications containing alcohol, mouthwashes, or food preparations) during and up to five days after administration may result in a disulfiram-like reaction. This reaction may cause flushing, sweating, headache, and increased heart rate. Avoid alcohol during this period.

Notify your doctor if you experience severe or bloody stools while taking Cefglobe S Injection.

Before taking this medication, inform your doctor if you have liver disorders, bowel diseases, or clotting disorders.

This drug should be used only when necessary during pregnancy. As this medication passes poorly into breast milk, caution should be exercised during breastfeeding. Consult your physician for further guidance.

Uses

Respiratory Tract Infections Urinary Tract Infections Intra-abdominal Infections Septicemia Meningitis Skin and Soft Tissue Infections Bone and Joint Infections Endometritis

How it works

Cefoperazone is an antibiotic that works by interfering with bacterial cell wall synthesis, leading to the destruction of the bacteria. Sulbactam, the beta-lactamase inhibitor, helps inactivate the beta-lactamase enzymes produced by certain bacteria. This prevents the breakdown of cefoperazone by these enzymes, enhancing its effectiveness against resistant bacteria.

How to Use

Do not self-administer the Cefglob S injection. Your doctor will decide the duration and dose of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion or intramuscular Injection, and you will be monitored carefully for unwanted side effects.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Nausea, vomiting Headache Diarrhea Allergic reactions Anemia Abnormal liver function Injection site reactions

Expert Tips

Maintaining good hand hygiene by washing your hands regularly helps to prevent the spread of infections to others. Do not skip doses or stop the medication suddenly, even if you start feeling better. Completing the full course of treatment is important to effectively treat the infection and prevent the development of antibiotic resistance.

References

  1. Pfizer Limited, [Revised on April 2020] [ Accessed on 27th June 2021], https://labeling.pfizer.com/ShowLabeling.aspx?id=14800
  2. Pfizer, US Food and Drug Administration, [Revised on March 2015] [ Accessed on 27th June 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf
  3. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Penicillins, cephalosporins, and other beta-lactam antibiotics, 12th edition, 2011, 1499.
  4. KD Tripathi, Essentials of Medical Pharmacology, Beta-lactam antibiotics, 7th edition, 2013, 728.

Safety Advice

Pregnancy: Consult your doctor Cefglob S injection should be taken if it is necessary during pregnancy. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment.

Lungs: safe Cefglob S injection is safe and can be prescribed for patients with lung problems. Consult your physician if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Cefglob S injection because the medicine passes into the breast milk in small amounts and harms the baby. Caution is advised in these conditions.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS