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Celstemx 24mg Injection

Salt Composition: PLERIXAFOR

₹18841.00₹29906.25

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Celstemx 24mg injection is an antineoplastic containing the active ingredient Plerixafor. It is used in collecting blood stem cells, storage, and transplantation. It is also used in lymphoma (WBC cancer), multiple myeloma (plasma cell cancer in bone marrow), or a solid tumor. Inform your doctor if you have or had any heart disease. Before starting the treatment, inform your doctor if you have high WBC counts, low platelet counts, or a history of usual lightheaded or fainting, especially before injection. It is not advised to take this medicine for stem cell mobilization if you have leukemia. Do not take this tablet if you are allergic to Plerixafor any other medicine ingredients. Notify your doctor if you have kidney disorders; your doctor may adjust the dose of the Celstemx 24mg if you have existing kidney disease. Your doctor may also perform a regular blood test to monitor the blood cell count. Do not take this tablet if you are pregnant or planning to get pregnant or think you might be pregnant, or if you are breastfeeding. It is recommended to use effective contraception. Report to your doctor if you experience any side effects like rashes or swelling around your eyes, a change in breathing (lack of oxygen), or pain in the abdomen (upper left) or left shoulder.

Uses

Collect blood stem cells Lymphoma and multiple myeloma in adults Lymphoma or solid tumors in children (aged between 1 to 18)

How it works

Celstemx 24mginjection works by blocking a protein called CXCR4 (chemokine receptor) on stem cells, which helps them move from the bone marrow into the bloodstream. By blocking CXCR4, Celstemx 24mgcauses the stem cells to be released into the bloodstream, where the stem cells can be collected and isolated using a machine and stored for transplantation.

How to Use

Celstemx 24mg injection is administered as a subcutaneous injection (under your skin). If this drug is recommended for you, it will be given by a doctor. Do not self-administer. Your doctor will choose the dosage and administration frequency based on the condition because it differs from person to person.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Rashes and swelling around the eyes Difficulty in breathing Faintness Upper left abdomen pain Left shoulder pain Common Diarrhea Redness or irritation in the injection site Low RBC count (anemia) Constipation, indigestion Dry mouth, numbness Joint pains Sweating Difficulty in sleeping Headache

Expert Tips

You need to tell your doctor if you have any kidney disorders before taking Celstemx 24mg Injection. Your physician may decide to adjust the dose or delay treating you depending on your kidney function. Please consult your doctor before starting this injection, and getting suggestions about fertility concerns from your doctor is recommended. Your doctor may take regular blood tests to monitor your liver function and blood cell count.

References

  1. Genzyme Corporation, U.S. Food & Drug Administration [Revised on Dec 2017] [Accessed on 13th April 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/022311s018lbl.pdf
  2. Seacross Pharmaceuticals Limited, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 20th April 2023], Plerixafor Seacross 20 mg/ml solution for injection - Patient Information Leaflet (PIL) - (emc) (medicines.org.uk)
  3. James L. Zehnder, Agents Used in Cytopenias; Hematopoietic Growth Factors, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 591- 607.

Safety Advice

Pregnancy: Consult your doctor Celstemx 24mg injection can cause harm to your unborn baby. Report to your doctor if you are pregnant or planning to get pregnant before taking the Plerixafor injection. Use effective contraception.

Lungs: Consult your doctor Consult your doctor immediately if you experience any symptoms like difficulty in breathing. Contact your doctor for more lung-related concerns.

Breastfeeding: unsafe You must not breastfeed while being treated with Celstemx 24mg injection. Inform your physician if you are breastfeeding before taking this treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS