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Celtranz 500mg Injection

Salt Composition: TRANEXAMIC ACID

₹58.00₹73.20

Inclusive of all taxes

Categories: Others

Conditions: Others

Product Introduction

Celtranz 500mg Injection contains tranexamic acid, an antifibrinolytic medicine that prevents the breakdown of blood clots. It is indicated in patients with haemophilia (a disorder where blood does not clot normally) for short-term use to prevent blood loss. It is effective for preventing or managing excessive bleeding associated with fibrinolytic medications, cardiopulmonary bypass surgery, dental extraction, tonsillectomy, or prostate removal, as well as heavy menstrual bleeding in women. Do not use this medication if you are allergic to tranexamic acid or any component of Celtranz 500mg Injection. Inform your doctor if you have a history of kidney problems, blood disorders, or seizures. You should also inform your physician if you have any liver disorders. Tell your physician about all medications you are taking before starting treatment.

Uses

Prevent bleeding in hemophilia patients after tooth extraction Management of gastrointestinal bleeding Managing heavy menstrual bleeding in females. Management of bleeding following surgery

How it works

Celtranz 500mg Injection acts by stopping the breakdown of blood clots. It does this by blocking the lysine binding site on a plasminogen protein. This prevents plasminogen from breaking down fibrin, a key component of blood clots, and helps to maintain clot stability. In simpler terms, it helps to keep blood clots intact and prevents excessive bleeding.

How to Use

Treatment should be started under the guidance of a healthcare provider. It will be injected directly into your veins (intravenous) by your healthcare provider. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Severe allergic reactions (skin rash, lumps) Breathing difficulties swelling of the face, neck, and legs Weakness on one side of the body Blood clot formation Common Nausea, vomiting, diarrhea Giddiness Low blood pressure Visual disturbances

Expert Tips

Patients who take this medication for an extended period may experience color vision abnormalities and other problems linked to their eyes. Thus, it is necessary for individuals receiving ongoing, long-term treatment to undergo routine ophthalmologic exams. Talking to your doctor is crucial if you have renal issues because the kidneys significantly eliminate Celtranz 500mg Injection. Dosage modifications may be necessary. Inform your physician if you have had blood in your urine, which could indicate a clot in your upper urinary tract. Blood clots are more likely to occur in women using hormonal birth control pills. Talk to your doctor about any worries you may have. Some herbal supplements may interact with this medication, particularly those with potential blood-thinning effects (e.g., ginkgo biloba, garlic, ginger). Inform your healthcare provider about the supplements you are taking.

References

  1. Industria Farmaceutica Galenica Senese S.r.l., Electronic medicines compendium “(EMC)” , [Revised on March 2020 ] [Accessed on December 2023] https://www.medicines.org.uk/emc/files/pil.8835.pdf
  2. Pfizer Injectables ,US Food and Drug Administration (FDA) [Revised on January 2021] [Accessed on December 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019281s047lbl.pdf
  3. Pfizer Manufacturing, [Revised on June,2023] [Accessed on December 2023] https://labeling.pfizer.com/ShowLabeling.aspx?id=15029
  4. KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Coagulation, Bleeding and Thrombosis, 8th Edition, 2019, 659-681.
  5. Goodman and Gilman's The Pharmacological Basis of Therapeutics, Blood Coagulation and Anticoagulant, 13th Edition, 2017,596

Safety Advice

Pregnancy: Consult your doctor Celtranz 500mg Injection is known to pass the placenta. Therefore, it is used cautiously; your physician will provide it to you only when necessary.

Lungs: Consult your doctor Patients with lung diseases should consult their healthcare providers before using Celtranz 500mg Injection to ensure personalized decision-making based on their specific health conditions.

Breastfeeding: Consult your doctor Celtranz 500mg Injection is excreted in breast milk. Therefore, the use of this medication during breastfeeding is not advisable. Tell your doctor if you are breastfeeding before taking this medication.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS