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Chemoblast 10mg Injection

Salt Composition: VINBLASTINE

₹232.00₹266.50

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Chemoblast 10mg Injection

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Chemoblast 10mg Injection is an anti-cancer drug belonging to the class of mitotic inhibitors, containing the active ingredient vinblastine. This medication is used in combination with other medicines for the treatment of Hodgkin's and non-Hodgkin's lymphoma, testicular cancer, breast cancer, and Kaposi's sarcoma. Hodgkin's disease and non-Hodgkin's disease refers to the type of blood cancers. This injection should be used with caution in patients with a history of nerve damage, respiratory disease, or gastrointestinal disorders. Special care is needed if you are taking other medicines, as some could interact with this drug. For example the use of erythromycin may increase the side effects of this drug. In case if you are undergoing radiotherapy in the liver area, your doctor will delay giving you this medicine. During the treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes and kidney parameters to prevent serious complications. This medicine has the potential to cause heart problems when combined with other anticancer medicine like bleomycin or cisplatin. Report to your doctor if you experience any hypersensitive reactions like itchy skin or rashes, while taking this medicine. As there is a risk of birth defects, women of childbearing potential should use effective contraception methods during treatment with this drug. If you're pregnant or breastfeeding women, you may plan to have a baby or think you may be pregnant. Please consult with your doctor for more advice before taking this medicine. Do not drive or use machines if you experience any side effects which may lessen your ability to do so. It is advised not to use this injection if you are allergic to this drug or any of its ingredients, in case you have a bacterial infection which is not under control, and if your blood tests show that you do not have enough WBC to fight infection. This drug may lead to changes in your blood cells, so your doctor will take blood samples to monitor for these and also to check how well your liver is working. Inform to the doctor if you have been diagnosed with liver disorders, heart failure, high blood cholesterol levels, or hypertension before starting this treatment.

Uses

Chemoblast 10mg injection has been indicated for treating, Hodgkin’s lymphoma Non-Hodgkin’s lymphoma Testicular cancer Breast cancer Kaposi’s sarcoma

How it works

It works by disrupting the formation of microtubules in cells. Microtubules are structures that help to support and shape cells, as well as transport molecules within cells. In cancer cells, microtubules play a key role in cell division and growth. By interfering with microtubule formation, this drug disrupts the ability of cancer cells to divide and grow, ultimately leading to their death.

How to Use

It should only be administered by a trained doctor or nurse experienced in giving chemotherapy. This medication is injected directly into a vein through a needle or catheter. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Severe allergic reactions (difficulty in breathing or swallowing, swelling of hands, feet, lips, mouth, or throat, itchy rash) Swelling or pain at the site of injection (during or immediately after the injection) Common Low blood counts Convulsions Mental depression Tiredness Diarrhea Loss of appetite Nausea, vomiting Stomach cramps Hair loss

Expert Tips

This medicine can weaken the immune system, making patients more susceptible to infections. Patients should take steps to avoid contact with sick people and practise good hygiene, such as washing their hands frequently. Patients should also avoid activities that could increase their risk of injury or bleeding, such as contact sports or using sharp objects. This drug makes the skin more sensitive to sunlight, leading to sunburn, blistering, or skin discoloration. It's important to use sunscreen and protective clothing while being exposed to sunlight. It is recommended to limit your alcohol intake or avoid it altogether while taking Chemoblast 10mg injection.

References

  1. Hospira UK Limited, Electronic medicines compendium (EMC), [Revised on Sept 2020][ Accessed on 4th April 2023], https://www.medicines.org.uk/emc/files/pil.1422.pdf
  2. DBL vinblastine injection - pfizer. Available at: https://labeling.pfizer.com/ShowLabeling.aspx?id=12288 [ Accessed on 4th April 2023].
  3. Vinblastine injection -NPS MedicineWise. Available at: https://www.nps.org.au/assets/medicines/aea96da5-9c46-482b-9add-a53300ff05d1.pdf [ Accessed on 4th April 2023].
  4. HY Yap; Vinblastine given as a continuous 5-day infusion in the treatment of refractory advanced breast cancer; Cancer Treatment Reports; Published on March 1980;[ Accessed on 4th April 2023]; https://pubmed.ncbi.nlm.nih.gov/7407762/
  5. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1706.
  6. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.

Safety Advice

Pregnancy: unsafe Chemoblast 10mg injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Lungs: Consult your doctor It is not known whether Chemoblast 10mg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Chemoblast 10mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS