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Cleft 20mg Tablet

Salt Composition: LEFLUNOMIDE

₹194.00₹227.72

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Cleft 20mg Tablet

Categories: Gastroenterology

Conditions: Arthritis

Product Introduction

Cleft 20mg Tablet is an antirheumatic medication that belongs to a class of drugs called disease-modifying antirheumatic drugs (DMARDs) containing the active ingredient Leflunomide. It is used to treat rheumatoid arthritis, a chronic inflammatory condition that affects the joints. It is also used in the treatment of psoriatic arthritis, which is a type of inflammatory arthritis that occurs in some individuals with psoriasis. Psoriatic arthritis affects the joints and can cause pain, swelling, stiffness, and reduced range of motion.

This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its components. Before taking Cleft 20mg Tablet, inform your doctor if you have a history of interstitial lung disease, tuberculosis, skin ulcers, unexplained chronic diarrhoea, liver problems, or kidney problems. Your doctor may perform certain tests for further diagnosis and prescribe a low dose if necessary.

Certain vaccinations may not be recommended while on treatment with this drug because it can affect the immune system, and this can impact the effectiveness or safety of vaccines. This drug remains in the body for a considerable period even after discontinuation. Therefore, it is important to discuss vaccination plans with your doctor before initiating treatment. If you are currently experiencing a severe infection, it may be necessary to delay or avoid starting Cleft 20mg Tablet treatment until the infection is resolved.

This drug is contraindicated during pregnancy because it can have harmful effects on a developing fetus and may also be present in breast milk. Drinking alcohol while taking this drug can further stress the liver and lead to liver toxicity or other complications. Avoid consuming alcohol during treatment.

Uses

Treatment of rheumatoid arthritis Treatment of psoriatic arthritis

How it works

Cleft 20mg Tablet works by suppressing the immune system and reducing inflammation. It inhibits the activity of certain immune cells called lymphocytes, which are involved in the inflammatory process.

How to Use

Take the Cleft 20mg Tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Serious allergic reactions (difficulty breathing, feeling dizzy or light-headed, weakness) Skin rash or ulcers in the mouth, bruising, pale skin Yellow discoloration of eyes and skin, abdominal pain Infections (fever, sore throat, cough) Tingling or pain in hands or feet Common Loss of appetite, weight loss Low white blood cells Mild increase in blood pressure Diarrhea Nausea, vomiting Hair loss Dry skin, itching

Expert Tips

Since this medication aims to reduce joint pain, swelling, and stiffness. It may take several weeks or months to experience the full benefits of Cleft 20mg Tablet, so be patient and continue taking it as directed.

References

  1. Aspire Pharma Ltd, Electronic medicines compendium (EMC), [Revised on June 2022] [ Accessed on 17th August 2023], https://www.medicines.org.uk/emc/files/pil.5399.pdf
  2. Sanofi-aventis US LLC, US Food and Drug Administration, [Revised on July 2011] [ Accessed on 17th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020905s022lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1014.
  4. KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 212.

Safety Advice

Pregnancy: Consult your doctor If you are pregnant, suspecting, or planning for the pregnancy, consult your doctor for more advice before taking Cleft 20mg Tablet .

Lungs: Consult your doctor It is unknown whether Cleft 20mg Tablet is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.

Breastfeeding: unsafe Taking Cleft 20mg Tablet while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS