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Clexane 60mg Injection
Salt Composition: ENOXAPARIN
- Manufacturer: SANOFI INDIA LTD
- Pack Size: 1 PREFILLED SYRINGE(s)
- Dosage Form: INJECTION
- Strength: 60MG
- Prescription Required
- Storage: Store Clexane 60mg Injection below 25 °C. Do not freeze Keep it out of reach from children. Protect them from light and moisture.
₹571.00₹705.41
Inclusive of all taxes
Product Introduction
Clexane 60mg Injection is an anticoagulant belonging to the low molecular weight heparin (LMWH) class. It contains Enoxaparin as the active ingredient. It is indicated for treatment of severe blood clots and prevention of deep vein thrombosis following abdominal surgery, hip replacement surgery, knee replacement surgery, and in patients with severe immobility. This injection reduces the risk of further cardiac complications in patients with unstable angina and non-Q wave myocardial infarction.
Clexane 60mg Injection is contraindicated in patients with active bleeding, hypersensitivity, or allergy to the active ingredient. It should not be used in those with a history of heparin-induced thrombocytopenia. Before starting treatment, inform your physician if you have allergies to Enoxaparin, heparin, benzyl alcohol, or pork products. Your healthcare provider will conduct regular monitoring for signs of bleeding. If you have kidney problems, this must be communicated to your healthcare practitioner. Use is not recommended in children and adolescents below 18 years of age. Clexane 60mg Injection is not suitable if you require procedures involving neuraxial anaesthesia or spinal puncture.
Increased monitoring is recommended in elderly patients and those with low body weight due to elevated bleeding risk. Inform your physician if you are pregnant, breastfeeding, or planning pregnancy. In pregnant patients with artificial heart valves, Clexane 60mg Injection may increase bleeding risk and requires close clinical supervision. Hemostatic drugs should not be used concurrently unless absolutely necessary. Provide your physician with a complete list of all medications you are taking, including herbal and vitamin supplements, prior to commencing treatment.
Uses
Clexane 60mg Injection is used in the treatment of the following: Deep vein thrombosis Prophylaxis of venous thrombo-embolism Unstable angina ST-segment Elevation Myocardial Infarction (STEMI) Prevention of blood clots during surgeries
How it works
Clexane 60mg Injection binds to the antithrombin to form a complex. Antithrombin is a protein that blocks the formation of abnormal blood clots. This drug mainly prevents the activation of factor Xa, eventually preventing clot formation. It is commonly used for the prevention and treatment of conditions associated with increased risk of blood clots.
How to Use
Clexane 60mg Injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered as an intravenous injection into a vein. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects of Clexane 60mg Injection are: Severe allergic reactions (swelling of lips, tongue, or throat, difficulty breathing, or swallowing) Too much bleeding (weakness, being pale, dizziness with headache, or unexplained swelling) Blockage of blood vessels (pain, redness, or swelling in the legs, or coughing up blood) Rash of dark red spots under the skin Common side effects of Clexane 60mg Injection are: Bleeding Bruising more easily Low blood cell counts Headache Itchy red skin Edema Pain at the injection site Pink patches on the skin
Expert Tips
Clexane 60mg Injection can cause bleeding and many undesirable side effects; hence it is advised to get adequate rest during the treatment. Eat a well-balanced diet. Apply a cool compress at the injection site to reduce pain and irritation. Clexane 60mg Injection should not be stopped suddenly without first talking to your doctor because doing so may raise your risk of blood clots. Aspirin and other non-steroidal anti-inflammatory medicines (NSAIDs) may increase the risk of bleeding when combined with Clexane 60mg Injection, so it is not recommended to take them without first talking to your doctor. Keep away from activities that put you at higher risk of bleeding or getting hurt, like contact sports and activities. Foods high in Vitamin K may have an impact on blood clotting and may interfere with the way anticoagulant drugs like Clexane 60mg Injection. It is recommended to eat leafy green vegetables, asparagus, Brussels sprouts and soybean oil in moderation. It is advised to monitor your platelet count regularly.
References
- 1. Rovi Pharma Industrial ServicesElectronic Medicines Compendium (EMC), [Revised on Apr 2022], [Accessed on March 2024], https://www.medicines.org.uk/emc/files/pil.9331.pdf 2. Sanofi, [Revised on Apr 2022] [Accessed on March 2024], https://products.sanofi.us/lovenox/lovenox.pdf 3. Sanofi India Limited, Central Drugs Standard Control Organisation (CDSCO), [Revised on Dec 2018], [Accessed on March 2024], https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadPrescribingInfo/1CLEXANE-SANOFI.pdf 4. KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Coagulation, Bleeding and Thrombosis, 8th Edition, 2019, 659-681. 5. https://www.ema.europa.eu/en/documents/product-information/inhixa-epar-product-information_en.pdf
Safety Advice
Pregnancy: Consult your doctor Before beginning therapy with Clexane 60mg Injection, tell your doctor if you are pregnant, suspect you are pregnant, or are planning to become pregnant. It is not known that Clexane 60mg Injection interferes with pregnancy.
Lungs: Consult your doctor It is unknown whether Clexane 60mg Injection is safe for patients with lung problems. Consult your doctor if you have lung disease before starting the treatment.
Breastfeeding: Consult your doctor It is unknown if Clexane 60mg Injection is excreted unaltered in breast milk. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.