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Combinib 250mg Tablet
Salt Composition: LAPATINIB
- Manufacturer: CIPLA LTD
- Pack Size: 30 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 250MG
- Prescription Required
- Storage: Store below 30°C and away from light.
₹5512.00₹8228.00
Inclusive of all taxes
Product Introduction
Combinib 250mg Tablet contains the active ingredient lapatinib. It is indicated for the treatment of advanced breast cancer and may be used alone or in combination with other medications. It is effective against cancer cells sensitive to hormones and rapidly multiplying cancer cells that express high levels of the human epidermal growth factor receptor-2 protein. Common side effects during treatment with Combinib 250mg Tablet include nausea, vomiting, tiredness, weakness, itching, dry skin, loss of appetite, indigestion, constipation, mouth ulcers, stomach pain, difficulty in sleeping, joint or back pain, cough, breathing problems, and headache. Severe allergic reactions, skin rashes, and heart, liver, and lung problems require immediate medical attention. Inform your healthcare provider at the first sign of diarrhoea or dehydration. Blood pressure should be monitored regularly while taking Combinib 250mg Tablet. If diarrhoea occurs during treatment, maintain adequate fluid intake, consume low-fat high-protein foods, and avoid milk products and herbal supplements.
Uses
Treats advanced or HER2 Positive metastatic breast cancer.
How it works
Combinib 250mg Tablet acts against the enzyme called tyrosine kinase. It prevents the Human epidermal growth factor receptor protein (HER2) and Epidermal growth factor receptors (EGFRs) from signaling, which are produced by breast cancer cells. It kills cancer cells and slows down their growth.
How to Use
Take Combinib 250mg Tablet exactly as prescribed by your doctor. Take this medicine at least 1 hour before or after taking the food. Swallow the tablet and do not crush, open, or dissolve them.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them. Serious Diarrhea Severe allergic reactions Skin rash Heart problems Common Loss of appetite Nausea, vomiting Tiredness, weakness Indigestion Constipation Sore mouth or mouth ulcers Stomach pain Trouble sleeping Back pain Pain in the hands and feet Joint or back pain Cough, breathlessness Headache Nose bleed Hot flush Unusual hair loss Dry skin and itching
Expert Tips
Combinib 250mg Tablet can cause severe diarrhea, so it is advised to take plenty of water during the treatment. Eat a well-balanced diet. Avoid consuming grapefruit juice while on treatment with Combinib 250mg Tablet as it affects how the medicine works. This medication makes your skin sensitive to the sun and increases the risk of skin rashes. Avoid spending more time in the sunlight, and ensure that you always apply sunscreen with a good SPF before stepping out. Wash your skin with a soap-free cleanser.
References
- 1. Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976. 2. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936. 3. Novartis Europharm Limited, Electronic medicines compendium (emc), [ Revised on March 2022] [ Accessed on 19th August 2022], https://www.medicines.org.uk/emc/files/pil.6292.pdf 4. GlaxoSmithKline, US Food & Drug Administration, [ Accessed on 19th August 2022] , https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022059s007lbl.pdf
Safety Advice
Pregnancy: unsafe It is not safe to consume Combinib 250mg Tablet while you are pregnant. Consult your doctor and use a reliable contraception method to avoid becoming pregnant during this treatment.
Lungs: Consult your doctor Talk to your doctor if you have any lung conditions before starting treatment with Combinib 250mg Tablet.
Breastfeeding: unsafe Combinib 250mg Tablet is unsafe during breastfeeding as this medication tends to pass into the breast milk and affect the baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.