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Comtripsy 15mg Tablet
Salt Composition: TRIFLURIDINE AND TIPIRACIL
- Manufacturer: INTAS PHARMACEUTICALS LTD
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 15MG+6.14MG
- Prescription Required
- Storage: Keep Comtripsy 15mg Tablet out of sight and reach of children. Store at room temperature (20°C - 25°C).
₹2813.00₹3515.62
Inclusive of all taxes
Product Introduction
Comtripsy 15mg Tablet is an anticancer medication containing trifluridine and tipiracil as active constituents. It is indicated for treatment of adults with metastatic colorectal cancer when other treatment options are unsuitable. Trifluridine works by inhibiting cancer cell growth, while tipiracil prevents trifluridine degradation and extends its therapeutic activity. Cancer occurs when cells multiply uncontrollably and abnormally. This medicine is not recommended for patients under 18 years of age. Do not use this medicine if you are allergic to trifluridine, tipiracil, or any other ingredients in the formulation. Prior to commencing treatment, inform your doctor if you have renal or hepatic impairment or lactose intolerance. This treatment may cause side effects including neutropenia (decreased white blood cells), anaemia (decreased red blood cells), and gastrointestinal disturbances. Report any side effects or symptoms to your doctor. Dose adjustment is necessary in patients with renal impairment. Inform your doctor if you are pregnant or planning pregnancy; this medicine may harm the foetus, therefore both males and females should use contraception during treatment and for six months after treatment completion.
Uses
Metastatic colorectal cancer
How it works
Trifluridine interferes with the DNA synthesis of cancer cells and inhibits the growth of cancer cells. Tipiracil stops the body from breaking down Trifluridine and increases its exposure.
How to Use
Take Comtripsy 15mg Tablet as advised by your physician. Usually, this medicine will be taken as a whole with a glass of water. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking this medicine if your doctor advises you to stop.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Low white blood cell count (fever, chills) Anemia (shortness of breath, tiredness) Diarrhea, vomiting, abdominal pain Unusual bleeding or bruising Severe gastrointestinal problem Common Lack of appetite Nausea Hair loss Weight loss Changes in taste Constipation Swelling in hands or feet or mucous membranes Mouth pain Itchy dry skin A lower level of albumin Increased bilirubin Increase liver enzymes
Expert Tips
Notify your doctor if you are intolerant to sugar, as this medicine contains lactose. Your doctor may adjust the dosage if you are an inpatient with a kidney condition. Comtripsy 15mg Tablet come in two strengths, usually given twice a day. Your doctor may take a blood test before each test. Discuss the effective contraception method with your doctor.
References
- 1. Les Laboratories Servier, Electronic medicines compendium (EMC), [Revised on Dec 2020] [Accessed on 25th April 2023], https://www.medicines.org.uk/emc/files/pil.7309.pdf 2.Taiho Oncology, US Food, and Drug Administration, [Revised on Feb 2019] [ Accessed on 25th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/207981s008lbl.pdf 3.Celeste B Burness, Sean T Duggan; Trifluridine/Tipiracil: A Review in Metastatic Colorectal Cancer; Drugs; Published on Sep 2016; Accessed on 03/03/2022; https://pubmed.ncbi.nlm.nih.gov/27568360/
Safety Advice
Pregnancy: unsafe Comtripsy 15mg Tablet are unsafe during pregnancy as they may harm the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment. Use effective contraception.
Lungs: Consult your doctor It is unknown whether Comtripsy 15mg Tablet are safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Breastfeeding: unsafe Taking Comtripsy 15mg Tablet while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment. Therefore, talk with your doctor to get more information.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.