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Comtripsy 20mg Tablet
Salt Composition: TRIFLURIDINE AND TIPIRACIL
- Manufacturer: INTAS PHARMACEUTICALS LTD
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 20MG+8.19MG
- Prescription Required
- Storage: Keep Trifluridine & Tipiracil tablet out of sight and reach of children. Store at room temperature (20°C - 25°C).
₹3985.00₹4687.50
Inclusive of all taxes
Product Introduction
Comtripsy 20mg Tablet (also known as Comtripsy 6.14mg/20mg Tablet) is an anticancer medication used to treat colon and rectum cancer that has spread to other parts of the body (metastatic stage). It contains Trifluridine and Tipiracil, where Trifluridine helps slow the growth of cancer cells and Tipiracil ensures it stays active longer in the body. This medicine is not recommended for patients under 18 years of age. Do not take Comtripsy 20mg Tablet if you are allergic to its ingredients. Inform your doctor if you have kidney or liver issues, are lactose intolerant, or are pregnant or planning pregnancy. Both men and women should use effective contraception during treatment and for six months after. Common side effects include low white blood cell and red blood cell counts and digestive issues. Your doctor may perform regular blood tests and adjust the dose, especially if you have kidney problems. Comtripsy 20mg Tablet is usually taken twice a day, in prescribed strength.
Uses
Metastatic colorectal cancer
How it works
Trifluridine interferes with the DNA synthesis of cancer cells and inhibits the growth of cancer cells. Tipiracil stops the body from breaking down Trifluridine and increases its exposure.
How to Use
Take Comtripsy 20mg Tablet as advised by your physician. Usually, this medicine will be taken as a whole with a glass of water. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking this medicine if your doctor advises you to stop.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.Comtripsy 20â¯mg side effects include Seriou Low white blood cell count (fever, chills) Anemia (shortness of breath, tiredness) Diarrhea, vomiting, abdominal pain Unusual bleeding or bruising Severe gastrointestinal problem Common Lack of appetite Nausea Hair loss Weight loss Changes in taste Constipation Swelling in hands or feet or mucous membranes Mouth pain Itchy dry skin A lower level of albumin Increased bilirubin Increase liver enzymes
Expert Tips
Inform your doctor if you are intolerant to sugar, as this medicine contains lactose. Dosage may be adjusted if you are an inpatient with a kidney condition. Comtripsy 20mg Tablet is available in two strengths and is usually taken twice daily. Your doctor may recommend a blood test before each dose. Discuss effective contraception methods with your doctor during treatment.
References
- 1. Les Laboratories Servier, Electronic medicines compendium (EMC), [Revised on Dec 2020] [Accessed on 25th April 2023], https://www.medicines.org.uk/emc/files/pil.7309.pdf 2.Taiho Oncology, US Food, and Drug Administration, [Revised on Feb 2019] [ Accessed on 25th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/207981s008lbl.pdf 3.Celeste B Burness, Sean T Duggan; Trifluridine/Tipiracil: A Review in Metastatic Colorectal Cancer; Drugs; Published on Sep 2016; Accessed on 03/03/2022; https://pubmed.ncbi.nlm.nih.gov/27568360/
Safety Advice
Pregnancy: unsafe Comtripsy 20mg Tablet are unsafe during pregnancy as they may harm the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment. Use effective contraception.
Lungs: Consult your doctor It is unknown whether Comtripsy 20mg Tablet are safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Breastfeeding: unsafe Taking Comtripsy 20mg Tablet while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment. Therefore, talk with your doctor to get more information.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.