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Cotrimoxazole DS Tablet

Salt Composition: SULFAMETHOXAZOLE,TRIMETHOPRIM

₹27.00₹32.81

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Cotrimoxazole DS tablet is a combination antibiotic containing sulphamethoxazole and trimethoprim. It is indicated for treatment of various bacterial infections including pneumonia, bronchitis, urinary tract infections, ear infections, and abdominal infections. The medication functions by inhibiting microbial growth to eliminate infection.

Cotrimoxazole DS tablet is contraindicated in patients with documented allergy to sulphamethoxazole, trimethoprim, or any ingredient in the formulation. It should not be used in patients with severe liver or kidney impairment or in infants under six weeks of age. Patients with a history of blood disorders associated with increased bleeding or bruising risk (thrombocytopenia) or porphyria should inform their doctor before use.

Prior to commencing Cotrimoxazole DS tablet, patients should notify their doctor of severe skin rash, blood disorders, history of allergies or asthma, folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency (a genetic disorder affecting red blood cells), or phenylketonuria (an inherited metabolic disorder). Similarly, inform your doctor if you have kidney or liver disease or are taking other medications. Patients with group A beta-haemolytic streptococcal infection, severe hyperkalaemia (elevated serum or plasma potassium levels), or risk of hyponatraemia (abnormally low blood sodium levels) should notify their doctor before initiating treatment. Regular blood count monitoring is advised during therapy. This medication is not recommended for use in children under 12 years of age.

Uses

Urinary tract infections Respiratory tract infections (bronchitis) Short-lived ear infections (acute otitis media) Infection of the lungs, brain, or skin (nocardiosis) Lung infections (pneumonia)

How it works

Sulfamethoxazole, Trimethoprim inhibits the production of Folic acid in bacteria which is essential for the growth and multiplication of bacteria and produces an antibacterial effect.

How to Use

Take the Cotrimoxazole DS tablet as your physician advises. Usually, the tablets will be taken with or without food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Skin reactions (Purplish spots or patches or blisters or peeling on the skin, high fever, joint pain, eye inflammation) Ulcers in the nose, mouth, throat, and genitals Common Infection affecting the mouth or vagina Headache Nausea Diarrhea Muscle cramps or pain Irregular heartbeats Unusual tiredness

Expert Tips

Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you have malnutrition or are suspected of porphyria. Do not plan for the pregnancy unless your doctor advises. At the same time, take Cotrimoxazole DS tablet unless your doctor advises. Talk to your physician if you have a worsening cough and shortness of breath. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Sulfonamides, Cotrimoxazole, and Quinolones, 7th edition, 2013, 706-708.
  2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for urinary tract infections, 12th edition, 2011, 1468-1470.
  3. Tillomed Laboratories Ltd, Electronic medicines compendium (emc), [ Revised on Feb 2023] [ Accessed on 20th June 2023], pil.11466.pdf (medicines.org.uk)
  4. AR Scientific, Inc, US Food and Drug Administration, [ Revised on June 2010] [ Accessed on 20th June 2023, https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/017377s067lbl.pdf

Safety Advice

Pregnancy: unsafe It is unsafe to consume Cotrimoxazole DS tablet during pregnancy. It should not be used during the first trimester of pregnancy. Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant before starting the treatment.

Lungs: Consult your doctor It is unknown whether Cotrimoxazole DS tablet is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: unsafe Consuming Cotrimoxazole DS tablet during breastfeeding is unsafe because the medicine is passed into the breast milk. Notify your doctor if you are breastfeeding before starting the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS