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Cytomab 100mg Injection

Salt Composition: RITUXIMAB

₹3315.00₹7520.99

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Cytomab 100mg Injection contains the active ingredient rituximab and is indicated for treatment of various conditions in adults. Cytomab 100mg may be administered as monotherapy or in combination with other medications for non-Hodgkin's lymphoma (a malignancy affecting B-lymphocytes) and chronic lymphocytic leukaemia (a common B-cell malignancy). It is also indicated for moderate-to-severe rheumatoid arthritis, used in combination with methotrexate, in adult patients. Additional indications include granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels affecting the lungs and kidneys) in adult and paediatric patients aged 2 years and above. Cytomab 100mg is also used for moderate-to-severe pemphigus vulgaris, an autoimmune disorder characterised by painful blisters on the skin and mucous membranes. The mechanism of action involves targeting and depleting specific B-cells responsible for abnormal immune responses or cancer growth, thereby assisting in disease control.

Uses

Cytomab 100mg uses are Non-hodgkin’s lymphoma (NHL) Chronic lymphocytic leukemia (CLL) Rheumatoid Arthritis Granulomatosis with polyangiitis or microscopic polyangiitis Pemphigus vulgaris

How it works

Rituximab is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes (a type of white blood cell). When this medicine binds to the B-cell, it induces cell death. The binding action blocks cell activation and growth and causes anticancer effects. It inhibits rheumatoid factor (RF) production, antigen presentation, T-cell activation, and certain signalling molecules in rheumatoid arthritis.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Cytomab 100mg side effects are Common Swelling in the face and body Diarrhea and nausea Itchy skin Anemia Muscle spasm Headache Urinary tract infection Fever, chills, and shivering Inflammation of nasal cavities Cough, sore throat Loss of hair Serious Increased or decreased blood pressure Chest pain Hypersensitivity reactions Hepatitis B viral infection Memory loss, trouble thinking, difficulty in walking

Expert Tips

Avoid vaccines before and during Cytomab 100mg injection therapy. Inform your physician if you have been vaccinated recently, as the injection may cause drug-induced immunosuppression. Report immediately to your doctor if you experience symptoms such as chest pain, breathing difficulties, stomach pain, or skin reactions. Inform your physician if you have kidney disease, as limited information is available on the safety of this medicine in patients with renal failure. Avoid vaccination with live virus vaccines before or during treatment, especially for patients with rheumatoid arthritis. Notify your healthcare professional if you have any active infection during treatment.

References

  1. Highlights of prescribing information; rituximab, (2021). Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/103705s5464lbl.pdf [Accessed 9 Mar. 2023].
  2. Package leaflet, Rituximab. (Revised on 2020). Available at: https://www.ema.europa.eu/en/documents/product-information/mabthera-epar-product-information_en.pdf [Accessed 9 Mar. 2023].
  3. Ahmed A. Negm & Daniel E. Furst, Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Lange's Basic & Clinical Pharmacology, 14th Edition, 2018, 642-666

Safety Advice

Pregnancy: unsafe Cytomab 100mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Lungs: Consult your doctor It is unknown whether Cytomab 100mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Cytomab 100mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS