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Dabigat 110mg Capsule
Salt Composition: DABIGATRAN ETEXILATE
- Manufacturer: NATCO PHARMA LTD
- Pack Size: 10 CAPSULE(s) IN A STRIP
- Dosage Form: CAPSULE
- Strength: 110MG
- Prescription Required
- Storage: Store at room temperature, between 20°C to 25°C (68°F to 77°F). Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹260.00₹305.63
Inclusive of all taxes
Product Introduction
Dabigat 110mg capsule contains dabigatran etexilate as its active component. It is used to prevent blood clots in patients at risk of stroke due to atrial fibrillation, an irregular heartbeat, and for the treatment and prevention of blood clots such as deep vein thrombosis (DVT) and pulmonary embolism (PE). As an anticoagulant, it works by inhibiting thrombin, the enzyme responsible for blood clotting, thereby preventing clot formation. Dabigat 110mg is a prodrug form that converts to dabigatran within the body. Unlike warfarin, which requires frequent monitoring and dose adjustments based on INR (International Normalized Ratio) measurements, Dabigat 110mg operates on a fixed dosage regimen. This eliminates the need for regular blood tests to assess effectiveness, offering greater convenience for both patients and healthcare providers. It has a relatively rapid onset of action, delivering a faster anticoagulant effect compared to other anticoagulants.
Patients with known hypersensitivity or allergy to dabigatran etexilate or any component of the formulation should not use this medication. As an anticoagulant, it increases the risk of bleeding and is contraindicated in patients with active pathological bleeding, including gastrointestinal bleeding, intracranial bleeding, or bleeding disorders. The medication is primarily eliminated through the kidneys and is contraindicated in patients with severe renal impairment except under specific circumstances where benefits outweigh risks and dose adjustment is made. The capsule contains lactose, and patients with lactose intolerance should exercise caution during use. They should inform their healthcare provider if they experience any gastrointestinal symptoms after beginning the medication.
Uses
Dabigat 110mg capsule is used in: Prevention and treatment of blood clots
How it works
Dabigat 110mg capsule, as an anticoagulant, exerts its therapeutic effects by inhibiting the activity of thrombin, a key enzyme in the blood clotting process. By doing so, it helps prevent the formation of blood clots, reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation. Additionally, it is effective in the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE).
How to Use
To use Dabigat 110mg capsule effectively, follow your healthcare provider's prescribed instructions. Typically, it comes in capsule form and should be taken orally, with or without food, as directed. Swallow the capsule whole with a full glass of water to ensure proper absorption. Avoid breaking, crushing, or chewing the capsules, as it may interfere with the medication's effectiveness. The dosage and frequency of administration will depend on your medical condition, such as atrial fibrillation or deep vein thrombosis, and your health status.
Side Effects
Dabigat 110mg capsule causes some side effects like all medications, although not everyone will experience them. Serious: Severe allergic reactions, including rash, itching, swelling, severe dizziness, or difficulty breathing Severe bleeding Liver problems Stroke or embolism Common: Upset stomach or indigestion Heartburn Nausea Diarrhea Mild bleeding, such as nosebleeds or bleeding gums Bruising more easily than usual
Expert Tips
Advice regarding Dabigat 110mg capsule is to always consult with a healthcare professional before starting or making any changes to your medication regimen. They can assess your medical history, evaluate potential risks and benefits, provide personalized guidance, and monitor your progress throughout treatment. Additionally, closely follow the instructions and recommendations your healthcare provider gives, promptly report any unusual or concerning symptoms, and communicate openly about any concerns or questions you may have. Precautions should be taken when using this medication in patients with liver or kidney impairment, as dosage adjustments or special monitoring may be required. Be vigilant for any signs of bleeding, such as unusual bruising, nosebleeds, or blood in urine or stools, and promptly inform your healthcare provider if you experience any of these symptoms. Avoid discontinuing the medication without medical advice, as sudden cessation may increase the risk of stroke. Before any medical procedures or surgeries, inform all healthcare providers about your use. Pregnant and breastfeeding individuals should consult with healthcare professionals before using this medication. Your healthcare professional is the best resource for ensuring safe and effective medication use.
References
- Spinler Sarah; The pharmacology and therapeutic use of Dabigat 110mg capsule; Journal of Clinical Pharmacology 2013; [Accessed on 24th July 2023], https://pubmed.ncbi.nlm.nih.gov/23400738/
- KP Garnock Jones; Dabigatran etexilate: A review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation; American Journal of Cardiovascular Drugs: drugs, devices and other inventions 2011; [Accessed on 24th July 2023], https://pubmed.ncbi.nlm.nih.gov/21265583/
- Boehringer Ingelheim Ltd; Electronic Medicines Compendium; [Revised: May 2020] [Accessed on 24th July 2023], https://www.medicines.org.uk/emc/files/pil.4703.pdf
- Boehringer Ingelheim Pharmaceuticals, Inc, US Food and Drug Administration, [Revised on Nov 2011], [Accessed on 24th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022512s007lbl.pdf
Safety Advice
Pregnancy: Consult your doctor Dabigat 110mg capsule is generally not recommended during pregnancy due to potential risks to the fetus. Pregnant women or those planning to become pregnant should discuss the risks and benefits of the medication with their healthcare provider.
Lungs: Consult your doctor If you have a lung condition and your healthcare provider has prescribed Dabigat 110mg capsule for another condition, it's essential to inform them about your lung condition and any other medical issues you may have.
Breastfeeding: Consult your doctor The safety of Dabigat 110mg capsule during breastfeeding is not well-established, and its use is generally not recommended. Breastfeeding women should consult their healthcare provider about the potential risks before using the medication.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.