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Dapaglyn S 10mg/100mg Tablet
Salt Composition: DAPAGLIFLOZIN,SITAGLIPTIN
- Manufacturer: ZYDUS CADILA
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 10MG+100MG
- Prescription Required
- Storage: Store at room temperature, between 20°C to 25°C. Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹214.00₹237.19
Inclusive of all taxes
Product Introduction
Dapaglyn S 10mg/100mg Tablet contains two active ingredients, Dapagliflozin and Sitagliptin, which work together to help manage type 2 diabetes mellitus. Since these medicines act through different mechanisms, their combination provides improved blood sugar control in suitable patients. Dapagliflozin belongs to the class of medicines known as sodium-glucose cotransporter-2 (SGLT2) inhibitors. It lowers blood glucose by promoting the removal of excess sugar through the urine, thereby reducing overall blood sugar levels. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps regulate blood glucose by increasing insulin release after meals and decreasing the production of glucagon, a hormone that raises blood sugar levels.
This combination may be especially beneficial for overweight or obese individuals with type 2 diabetes, as it can support blood sugar control while helping maintain a healthy body weight. Dapaglyn S 10mg/100mg Tablet is intended only for the treatment of type 2 diabetes and should not be used in patients with type 1 diabetes. People who are allergic to Dapagliflozin, Sitagliptin, or any other ingredient in this medicine should avoid using it.
Since the medication is mainly eliminated through the kidneys, it is not recommended for individuals with severe kidney impairment or end-stage renal disease. Patients taking dapagliflozin may have an increased risk of developing ketoacidosis during periods of severe illness, surgery, or significant physical stress. In such situations, a healthcare provider may advise temporarily stopping the medication. The safety of Dapaglyn S 10mg/100mg Tablet during pregnancy and breastfeeding has not been fully established. Therefore, pregnant or breastfeeding women should consult their doctor before taking this medicine.
Uses
Dapaglyn S 10mg/100mg Tablet is used to treat the following: Type 2 diabetes mellitus Obese individuals with type 2 diabetes
How it works
The Dapaglyn S 10mg/100mg Tablet in the treatment of type 2 diabetes provides a dual therapeutic effect by lowering blood glucose levels through different mechanisms: dapagliflozin reduces glucose reabsorption in the kidneys, leading to increased urinary excretion, while sitagliptin enhances insulin secretion and reduces glucagon production. This approach improves glycemic control, reduces the risk of hypoglycemia, and may offer cardiovascular and renal benefits.
How to Use
Dapaglyn S 10mg/100mg Tablet can be administered orally in tablet form. The specific usage instructions may vary depending on the condition being treated and the form of the medication. Oral tablets are typically taken with water, as directed by the healthcare provider.
Side Effects
Dapaglyn S 10mg/100mg Tablet cause some side effects like all medications, although not everyone will experience them. Serious Upper respiratory tract infections (colds, sore throat) Headache Stomach upset or nausea Diarrhea Hypoglycemia (low blood sugar) Joint pain (arthralgia) Common Genital yeast infections (vaginal or penile) Urinary tract infections (UTIs) Increased urination Thirst Dehydration Low blood pressure (hypotension) Dizziness or lightheadedness Increased levels of cholesterol and blood fats (hyperlipidemia)
Expert Tips
Take Dapaglyn S 10mg/100mg Tablet exactly as prescribed by your doctor for type 2 diabetes. Watch for infections in the genital or urinary area, and stay well-hydrated to avoid dehydration. Be aware of diabetic ketoacidosis symptoms like nausea, vomiting, or abdominal pain, and seek help if they appear. If you have kidney issues or are combining it with other diabetes medications, monitor for side effects carefully. Attend follow-up appointments regularly and discuss any concerns with your healthcare provider.
References
- Mohsin Kazi et al., Development and optimization of sitagliptin and dapagliflozin loaded oral self-nanoemulsifying formulation against type 2 diabetes mellitus, [Revised on 28/12/2021] [Accessed on 19/07/2023], https://pubmed.ncbi.nlm.nih.gov/33345632/
- Yue Sun et al., Effects of Dapagliflozin and Sitagliptin on Insulin Resistant and Body Fat Distribution in Newly Diagnosed Type 2 Diabetic Patients [Revised on 26/4/2020] [Accessed on 19/07/2023], https://pubmed.ncbi.nlm.nih.gov/32240122/
Safety Advice
Pregnancy: Consult Your Doctor The safety of Dapaglyn S 10mg/100mg Tablet during pregnancy has not been extensively studied, and limited information is available regarding its use in pregnant women. So it is advisable to consult a healthcare provider before using it.
Lungs: Consult Your Doctor Individuals with pre-existing lung conditions must inform their healthcare provider about their medical history before starting any new medication.
Breastfeeding: Consult Your Doctor The safety of Dapaglyn S 10mg/100mg Tablet during breastfeeding has not been well studied, and limited information is available regarding its excretion into breast milk. As a result, it is recommended to exercise caution when using it while breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.