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Dapaglyn S 5mg/50mg Tablet
Salt Composition: DAPAGLIFLOZIN,SITAGLIPTIN
- Manufacturer: ZYDUS CADILA
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 5MG+50MG
- Prescription Required
- Storage: Store at room temperature, between 20°C to 25°C. Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹174.00₹192.33
Inclusive of all taxes
Product Introduction
Dapaglyn S 5mg/50mg Tablet contains the active components dapagliflozin and sitagliptin, two medications used to treat type 2 diabetes mellitus. They operate through different mechanisms and may be combined to help control blood sugar levels in certain patients. Dapagliflozin belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors and works by lowering blood glucose levels and reducing overall blood sugar burden in the body. Sitagliptin is classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor. It regulates blood glucose levels by stimulating insulin release and reducing glucagon production, a hormone that raises blood sugar. This medication can be particularly beneficial for overweight or obese patients with type 2 diabetes, as it may help achieve and maintain a healthy body weight. It is indicated for treating type 2 diabetes only and should not be used to treat type 1 diabetes. Patients with known hypersensitivity or allergy to dapagliflozin, sitagliptin, or other components of this medication should not take it. The medication is primarily eliminated through the kidneys. Therefore, patients with severe renal impairment or end-stage renal disease should not use this medication. During periods of illness, surgery, or other stressful situations, there may be an increased risk of developing ketoacidosis, particularly in those taking dapagliflozin. Temporary discontinuation of this medication during such events may be necessary. Limited data exist on the safety of Dapaglyn S 5mg/50mg Tablet during pregnancy and breastfeeding. Pregnant or breastfeeding patients should consult their healthcare provider before using this medication.
How it works
The Dapaglyn S 5mg/50mg Tablet in the treatment of type 2 diabetes provides a dual therapeutic effect by lowering blood glucose levels through different mechanisms: dapagliflozin reduces glucose reabsorption in the kidneys, leading to increased urinary excretion, while sitagliptin enhances insulin secretion and reduces glucagon production. This approach improves glycemic control, reduces the risk of hypoglycemia, and may offer cardiovascular and renal benefits.
How to Use
Dapaglyn S 5mg/50mg Tablet can be administered orally in tablet form. The specific usage instructions may vary depending on the condition being treated and the form of the medication. Oral tablets are typically taken with water, as directed by the healthcare provider.
Side Effects
Dapaglyn S 5mg/50mg Tablet cause some side effects like all medications, although not everyone will experience them. Serious Upper respiratory tract infections (colds, sore throat) Headache Stomach upset or nausea Diarrhea Hypoglycemia (low blood sugar) Joint pain (arthralgia) Common Genital yeast infections (vaginal or penile) Urinary tract infections (UTIs) Increased urination Thirst Dehydration Low blood pressure (hypotension) Dizziness or lightheadedness Increased levels of cholesterol and blood fats (hyperlipidemia)
Expert Tips
Take Dapaglyn S 5mg/50mg Tablet exactly as prescribed by your doctor for type 2 diabetes. Watch for infections in the genital or urinary area, and stay well-hydrated to avoid dehydration. Be aware of diabetic ketoacidosis symptoms like nausea, vomiting, or abdominal pain, and seek help if they appear. If you have kidney issues or are combining it with other diabetes medications, monitor for side effects carefully. Attend follow-up appointments regularly and discuss any concerns with your healthcare provider.
References
- Mohsin Kazi et al., Development and optimization of sitagliptin and dapagliflozin loaded oral self-nanoemulsifying formulation against type 2 diabetes mellitus, [Revised on 28/12/2021] [Accessed on 19/07/2023], https://pubmed.ncbi.nlm.nih.gov/33345632/
- Yue Sun et al., Effects of Dapagliflozin and Sitagliptin on Insulin Resistant and Body Fat Distribution in Newly Diagnosed Type 2 Diabetic Patients [Revised on 26/4/2020] [Accessed on 19/07/2023], https://pubmed.ncbi.nlm.nih.gov/32240122/
Safety Advice
Pregnancy: Consult Your Doctor The safety of Dapaglyn S 5mg/50mg Tablet during pregnancy has not been extensively studied, and limited information is available regarding its use in pregnant women. So it is advisable to consult a healthcare provider before using it.
Lungs: Consult Your Doctor Individuals with pre-existing lung conditions must inform their healthcare provider about their medical history before starting any new medication.
Breastfeeding: Consult Your Doctor The safety of Dapaglyn S 5mg/50mg Tablet during breastfeeding has not been well studied, and limited information is available regarding its excretion into breast milk. As a result, it is recommended to exercise caution when using it while breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.