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Dapefy S 10mg/100mg Tablet

Salt Composition: DAPAGLIFLOZIN,SITAGLIPTIN

₹241.00₹300.94

Inclusive of all taxes

Categories: Others

Conditions: Diabetes Mellitus

Product Introduction

Dapefy S 10mg/100mg Tablet contains dapagliflozin and sitagliptin, two active components used to treat type 2 diabetes mellitus. These medications operate through different mechanisms and may be combined to help control blood sugar levels in certain patients. Dapagliflozin belongs to the sodium-glucose cotransporter 2 (SGLT2) inhibitor class and functions to lower blood glucose levels and reduce overall blood sugar burden in the body. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that regulates blood glucose levels by stimulating insulin release and reducing glucagon production, a hormone that raises blood sugar. This medication may be particularly beneficial for overweight or obese individuals with type 2 diabetes, as it can help achieve and maintain healthy body weight. It is indicated for treating type 2 diabetes only and should not be used to treat type 1 diabetes. Individuals with known hypersensitivity or allergy to Dapefy S 10mg/100mg Tablet or other components of these medications should not take them. The medication is primarily eliminated through the kidneys. Therefore, individuals with severe renal impairment or end-stage renal disease should not use this medication. During periods of illness, surgery, or other stressful situations, there may be an increased risk of developing ketoacidosis, particularly in those taking dapagliflozin. Temporary discontinuation of this medication during such events may be necessary. Limited data exists on the safety of Dapefy S 10mg/100mg Tablet during pregnancy and breastfeeding. Pregnant or breastfeeding individuals should consult their healthcare provider before using this medication.

Uses

Dapefy S 10mg/100mg tablets is used to treat the following: Type 2 diabetes mellitus Obese individuals with type 2 diabetes

How it works

The Dapefy S 10mg/100mg tablets in the treatment of type 2 diabetes provides a dual therapeutic effect by lowering blood glucose levels through different mechanisms: dapagliflozin reduces glucose reabsorption in the kidneys, leading to increased urinary excretion, while sitagliptin enhances insulin secretion and reduces glucagon production. This approach improves glycemic control, reduces the risk of hypoglycemia, and may offer cardiovascular and renal benefits.

How to Use

Dapefy S 10mg/100mg tablets can be administered orally in tablet form. The specific usage instructions may vary depending on the condition being treated and the form of the medication. Oral tablets are typically taken with water, as directed by the healthcare provider.

Side Effects

Dapefy S 10mg/100mg tablets cause some side effects like all medications, although not everyone will experience them. Serious side effects: Upper respiratory tract infections (colds, sore throat) Headache Stomach upset or nausea Diarrhea Hypoglycemia (low blood sugar) Joint pain (arthralgia) Common side effects: Genital yeast infections (vaginal or penile) Urinary tract infections (UTIs) Increased urination Thirst Dehydration Low blood pressure (hypotension) Dizziness or lightheadedness Increased levels of cholesterol and blood fats (hyperlipidemia)

Expert Tips

If you have prescribed Dapefy S 10mg/100mg tablets for type 2 diabetes, follow your healthcare provider's instructions carefully. Monitor for unusual symptoms, such as genital or urinary infections, and stay hydrated to prevent dehydration. Be aware of signs of diabetic ketoacidosis and seek medical attention promptly if needed. If you have kidney impairment or use sitagliptin with other diabetes medications, be cautious about potential side effects. Regularly attend follow-up appointments and communicate openly with your healthcare provider about any concerns or questions for a successful and safe diabetes management journey.

References

  1. Mohsin Kazi et al., Development and optimization of sitagliptin and dapagliflozin loaded oral self-nanoemulsifying formulation against type 2 diabetes mellitus, [Revised on 28/12/2021] [Accessed on 19/07/2023], https://pubmed.ncbi.nlm.nih.gov/33345632/
  2. Yue Sun et al., Effects of Dapagliflozin and Sitagliptin on Insulin Resistant and Body Fat Distribution in Newly Diagnosed Type 2 Diabetic Patients [Revised on 26/4/2020] [Accessed on 19/07/2023], https://pubmed.ncbi.nlm.nih.gov/32240122/

Safety Advice

Pregnancy: Consult your doctor The safety of Dapefy S 10mg/100mg tablets during pregnancy has not been extensively studied, and limited information is available regarding its use in pregnant women. So it is advisable to consult a healthcare provider before using it.

Lungs: Consult your doctor Individuals with pre-existing lung conditions must inform their healthcare provider about their medical history before starting any new medication.

Breastfeeding: Consult your doctor The safety of Dapefy S 10mg/100mg tablets during breastfeeding has not been well studied, and limited information is available regarding its excretion into breast milk. As a result, it is recommended to exercise caution when using it while breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS