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Dargen 25mcg Injection
Salt Composition: DARBEPOETIN ALFA
- Manufacturer: LUPIN LTD
- Pack Size: 1 PREFILLED SYRINGE(s)
- Dosage Form: INJECTION
- Strength: 25MCG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store in a refrigerator (2°C to 8°C). Do not freeze. Store in the original package to protect from light. Keep the injection away from the reach of children and pets. If you have missed any dosing appointments, inform your doctor and schedule immediately.
₹1425.00₹1899.38
Inclusive of all taxes
Product Introduction
Dargen 25mcg injection contains the active ingredient Darbepoetin Alfa, a hematopoietic growth factor medication. It is indicated for treatment of anemia in patients with chronic kidney disease and for anemia caused by chemotherapy in patients with certain types of cancer. Symptoms of anemia include fatigue, weakness, and shortness of breath.
Do not use Dargen 25mcg injection if you are allergic to Darbepoetin Alfa or any other ingredients in the formulation, or if you have uncontrolled blood pressure. Inform your physician if you have high blood pressure, anemia, a history of seizures, epilepsy, liver disease, or allergy to latex or hepatitis C. Inform your physician if you are pregnant or breastfeeding.
Substitute medications containing Erythropoietin include Erypro Safe, Zyrop, and Wepox, as advised by your physician.
Contact your physician immediately if you experience severe headache, dizziness, drowsiness, confusion, visual disturbances, nausea, vomiting, or seizures after administration of Dargen 25mcg injection.
The most commonly reported side effects are hypertension, shortness of breath, leg swelling, and cough.
Uses
Dargen 25mcg uses are: To treat anemia in chronic kidney failure To treat anemia caused by chemotherapy
How it works
Dargen 25mcg injection is an erythropoiesis-stimulating protein produced by recombinant DNA technology. It is closely related to erythropoietin and stimulates erythropoiesis by the same mechanism, and both agents bind to progenitor stem cells stimulating the production/differentiation of red blood cells. It works by causing the bone marrow to make more red blood cells.
Side Effects
Dargen side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Swelling in the face and body Low blood pressure Abdominal pain Shortness of breath cough Serious Heart problems Severe skin reactions Anemia Seizure attack Lung problems
Expert Tips
Follow your doctor’s exact instructions for dose and frequency; do not exceed them. This medicine is given as a subcutaneous injection; learn proper technique if self-administering. Rotate injection sites each time and keep track to avoid using the same area repeatedly. Do not shake the vial or syringe before use. Inform your doctor if you are pregnant, breastfeeding, or have conditions like heart disease, kidney problems, blood disorders, cancer, or a history of clots, stroke, or seizures.
References
- Aranesp solution for injection in pre-filled pen (SureClick) - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published March 2022. Accessed May 10, 2023. http://www.medicines.org.uk/emc/product/6958/smpc
- Darbepoetin Alfa.; Revised June 2011. Accessed May 10, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/103951orig1s5173_103951orig1s5258lbl.pdf
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Hematopoietic agents, 12th edition, 1071 - 1072.
- KD Tripathi, Essentials of Medical Pharmacology, Haematinics and Erythropoietin, 7th edition, 2013, 611.
Safety Advice
Pregnancy: Consult your doctor There are no adequate and well-controlled studies on the use of Dargen 25 in pregnant women. Inform your physician if you are pregnant, suspecting, or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is unknown whether inj Dargen 25 can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Dargen 25 mcg because the medicine passes into the breast milk in small amounts and may harm your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.