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Dash 50mg Tablet

Salt Composition: DASATINIB

₹1989.00₹5653.13

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Dash 50mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Dash 50mg tablet contains the active ingredient Dasatinib. It is prescribed for adults and children above one year of age with Chronic Myeloid Leukemia. This medicine is used to treat newly diagnosed Philadelphia chromosome-positive (Ph+) chronic myeloid leukaemia (CML) in the chronic phase and Ph+ acute lymphoblastic leukaemia in patients resistant to other therapies. Chronic Myeloid Leukaemia refers to a type of blood cancer in which the body produces too many white blood cells due to alteration in the Philadelphia chromosome. Acute Lymphoblastic Leukaemia is the most common form of blood cancer affecting children. In this condition, lymphocytes of white blood cells multiply too quickly and persist too long. Common side effects associated with Dash 50mg tablet include diarrhoea, headache, cough, rash, nausea, tiredness, vomiting, muscle pain, weakness, low appetite, and high or low blood pressure. Inform your doctor if these side effects are bothersome or persist. Inform your doctor if you are allergic to Dasatinib and its ingredients. Before starting treatment with this medication, inform your physician if you have liver or heart problems, breathing difficulties, chest pain, cough, hepatitis B infection, or bleeding problems. This medicine may cause severe reduction in the number of platelets, white blood cells, or red blood cells in the blood. Ensure your physician monitors your blood levels at regular intervals. Inform your healthcare professional about all medicines you take, including prescription and over-the-counter medicines, vitamins, antacids, and herbal supplements. It is not recommended for children below one year of age.

Uses

Dash 50mg tablet is indicated for the following conditions: Children and adults with chronic myeloid leukemia. Adults with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) with resistance to prior therapy.

How it works

Dash 50mg tablet works by preventing the abnormal protein from signaling the growth of cancer cells. This aids in preventing or reducing the spread of cancer cells.

How to Use

Take the tablet with or without food at the same time each day. Do not break, crush or chew the tablet. Your doctor will decide the dose and frequency of administration of Dash 50mg tablet based on your disease severity and other factors. Do not stop taking the tablet without consulting your healthcare professional.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Unusual bleeding or bruising Rapid heart rate Changes in consciousness or speech Breathlessness and swelling all over the body Fever or signs of infection Fluid retention Heart problems Myelosuppression Severe allergic reaction Common Diarrhea Headache Cough Rash Nausea, tiredness, vomiting Muscle pain, weakness Low appetite High or low BP

Expert Tips

It is advised to use effective contraceptives for both men and women taking Dash 50mg tablet during treatment and 30 days after the last dose. Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice blood in your urine or stools. If you take an antacid medicine, take it 2 hours before or 2 hours after taking this tablet.

References

  1. Bristol-Myers Squibb Pharma, Electronic Medicines Compendium (EMC), [Revised on Mar 2022] [Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.7745.pdf
  2. Bristol-Myers Squibb Company, [Revised on Jun 2021] [Accessed on 1st Dec 2022], https://packageinserts.bms.com/ppi/ppi_sprycel.pdf
  3. H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
  4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

Safety Advice

Pregnancy: unsafe Take the tablet with or without food at the same time each day. Do not break, crush or chew the tablet. Your doctor will decide the dose and frequency of administration of Dash 50mg tablet based on your disease severity and other factors. Do not stop taking the tablet without consulting your healthcare professional.

Lungs: Consult your doctor It is unknown whether Dash 50mg is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment.

Breastfeeding: unsafe It is not recommended to breastfeed while taking Dash 50mg tablet as it is not known whether this medication passes into breast milk. You should not breastfeed during treatment and for 2 weeks after your final dose.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS