Decitafect 50mg Injection

Decitafect 50mg injection contains the active substance decitabine, an antineoplastic drug that belongs to the class of DNA methylation inhibitors. It is indicated for the treatment of myelodysplastic syndrome, a group of conditions characterised by bone marrow production of misshapen blood cells and insufficient generation of healthy blood cells. It is also indicated for the treatment of acute myeloid leukaemia (AML). The mechanism of action involves inhibition of cancer cell growth.

Do not use this injection if you have a known allergy to decitabine or any other ingredient in this medicine. Inform your physician if you have an active infection, decreased blood cell count, liver disease, kidney disorder, or heart disorder. This medicine is not recommended for patients below 18 years of age.

This medicine can cause a serious immune reaction known as differentiation syndrome. Report to your physician if you experience symptoms including sudden difficulty in breathing, cough, fever, or body swelling.

Decitafect 50mg injection should not be used in pregnant women or women who are breastfeeding. Inform your physician if you are pregnant or breastfeeding. Use effective contraception throughout therapy to prevent pregnancy.

Common adverse reactions include decreased white blood cell count, decreased red blood cell count, decreased platelet count, and increased body temperature.

Myelodysplastic syndromes (MDS) Acute myeloid leukemia (AML)

Decitafect 50mg injection promotes hypomethylation of DNA and cellular differentiation or cell death after phosphorylation, direct incorporation into DNA, and inhibition of DNA methyltransferase. It works by helping the bone marrow produce normal blood cells and by killing abnormal cells in the bone marrow.

It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. It is given as an intravenous infusion drip (into your vein). This will take one hour. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Swelling in the face, hands, and feet Swelling and pain in the skin Discoloration of the skin Increased blood sugar levels Decreased albumin levels Abdominal pain, constipation Decrease in appetite Diarrhea, indigestion Nausea, vomiting Insomina, dizziness Pain in limbs Serious Heart problems Anemia Infection Bleeding Fluid in the lungs Pneumonia

Male patient with a female partner of reproductive potential to use effective contraception during the therapy and for 3 months after the last dose. Report symptoms of infection, anemia, or bleeding immediately to your doctor. Do not breastfeed during the treatment and for 1 week after the last dose. This medicine may cause infertility in both men and women, inform your doctor if you are planning for pregnancy before initiating the treatment. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. Your doctor may advise you to take certain tests to check for the effectiveness of the therapy.