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Denaxa 60mg Injection

Salt Composition: DENOSUMAB

₹8415.00₹17531.25

Inclusive of all taxes

Categories: Rheumatology

Conditions: Arthritis

Product Introduction

Denaxa 60mg Injection contains the active ingredient Denosumab and is indicated for treatment of osteoporosis, a condition characterised by diminished bone density and elevated fracture risk. It is also used to prevent skeletal-related events in patients with cancers including multiple myeloma and bone metastases. The medication functions by inhibiting RANK ligand, a protein that regulates osteoclast activity, thereby reducing bone resorption and maintaining bone strength. Clinical studies demonstrate that Denaxa 60mg improves bone mineral density and reduces fracture incidence, particularly in postmenopausal women and cancer patients with bone loss. The composition of Denaxa 60mg Injection includes Denosumab 60mg as the active component. Dosage is individualised by the prescribing doctor according to the patient's clinical condition and indication. Alternative preparations of Denosumab may be considered where appropriate. Denaxa 60mg is available as a prefilled syringe formulation. Pricing for Denosumab 60mg preparations varies according to manufacturer and geographic location.

Uses

DENAXA 60MG INJECTION uses in the treatment of the following condition: Osteoporosis Bone loss due to hormonal therapy in breast or prostate cancer Multiple myeloma (cancer affects plasma cells in the bone marrow) Bone metastases (cancer that spreads to bone)

How it works

Denaxa 60mg injection has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.

Side Effects

Denaxa 60mg injection can cause side effects like all medications, although not everyone who takes it will experience them. DENAXA 60MG INJECTION side effects are Serious: Osteonecrosis of the jaw (severe necrosis or death of jaw cells) Atypical femoral fractures Hypocalcemia (low blood calcium levels) Common: Injection site reactions Back pain Musculoskeletal pain Infections Abdominal pain Headache Hypophosphatemia (low blood phosphate levels)

References

  1. Amgen Ltd, Electronic medicines compendium (EMC), [ Revised on 13th May 2023], [ Accessed on 31st May 2023], https://www.medicines.org.uk/emc/files/pil.568.pdf
  2. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2010] [ Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/125320s007lbl.pdf
  3. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2022] [ Accessed on 31st May 2023], https://www.fda.gov/media/163378/download

Safety Advice

Pregnancy: Consult your doctor The safety of using Denaxa 60mg injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.

Lungs: Consult your doctor If you have a lung or respiratory disorders history, it is important to consult your healthcare provider before taking Denaxa 60mg injection.

Breastfeeding: Consult your doctor Whether Denaxa 60mg injection is excreted in milk is unknown. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS