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Denosurel 120mg Injection
Salt Composition: DENOSUMAB
- Manufacturer: RELIANCE LIFE SCIENCES PVT LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 120MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Denosurel 120mg Injection should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F). Do not freeze it. Keep in the original package. Keep away from light, moisture, and heat. Keep away from children and pets. Avoid taking double doses for missed doses.
₹14083.00₹39118.13
Inclusive of all taxes
Product Introduction
Denosurel 120mg Injection contains the active ingredient Denosumab. It is indicated for the treatment of osteoporosis, which is characterised by reduced bone density. It is also prescribed to prevent bone complications in patients with certain malignancies, including multiple myeloma and bone metastases. Denosurel 120mg Injection functions by inhibiting RANK ligand, a protein involved in bone tissue resorption. Clinical evidence demonstrates that it can substantially increase bone mineral density, thereby reducing fracture risk in postmenopausal women with osteoporosis and patients with cancer-associated bone loss. Renal function monitoring may be warranted in patients with moderate renal impairment. Denosurel 120mg Injection is contraindicated in individuals with known hypersensitivity or allergic reactions to any component of the formulation. Concurrent calcium and vitamin D supplementation is essential during treatment. The medication is not approved for use in children and adolescents. Safety and efficacy in the paediatric population have not been established; therefore, use is contraindicated in patients under 18 years of age. This medication should be used with caution in patients with pre-existing hypoparathyroidism, characterised by decreased parathyroid hormone levels.
Uses
Denosurel 120mg Injection is used in the treatment of the following condition: Osteoporosis Bone loss due to hormonal therapy in breast or prostate cancer Multiple myeloma (cancer affects plasma cells in the bone marrow) Bone metastases (cancer that spreads to bone)
How it works
Denosurel 120mg Injection has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.
How to Use
Denosurel 120mg Injection is given as an injection by healthcare professionals. The dosage and duration of treatment will be based on the individual's condition and response to the medication and should be determined by a healthcare provider.
Side Effects
Denosurel 120mg Injection can cause side effects like all medications, although not everyone who takes it will experience them. Serious: Osteonecrosis of the jaw (severe necrosis or death of jaw cells) Atypical femoral fractures Hypocalcemia (low blood calcium levels) Common: Injection site reactions Back pain Musculoskeletal pain Infections Abdominal pain Headache Hypophosphatemia (low blood phosphate levels)
Expert Tips
Attend all scheduled appointments and follow-up visits to monitor your response to treatment and address any concerns or side effects. Tell your doctor about your medical history, previous infection, liver disease, and kidney disease. Inform your healthcare provider about any allergies or hypersensitivity reactions you may have. Seek immediate medical attention if you experience severe allergic reactions or other serious side effects. Additionally, Denosurel 120mg Injection may affect calcium levels, so monitoring calcium levels and ensuring adequate calcium and vitamin D intake is important. Pregnant and breastfeeding women should consult a doctor before taking this medication. Avoid taking any vaccines during treatment. Regular dental examinations and good oral hygiene practices are recommended to minimize the risk of jaw osteonecrosis.
References
- Amgen Ltd, Electronic medicines compendium (EMC), [ Revised on 13th May 2023], [ Accessed on 31st May 2023], https://www.medicines.org.uk/emc/files/pil.568.pdf
- Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2010] [ Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/125320s007lbl.pdf
- Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2022] [ Accessed on 31st May 2023], https://www.fda.gov/media/163378/download
Safety Advice
Pregnancy: Consult your doctor The safety of using Denosurel 120mg Injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.
Lungs: Consult your doctor If you have a lung or respiratory disorders history, it is important to consult your healthcare provider before taking Denosurel 120mg Injection.
Breastfeeding: Consult your doctor Whether Denosurel 120mg Injection is excreted in milk is unknown. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.