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Duocef 3gm Injection

Salt Composition: CEFOPERAZONE,SULBACTAM

₹562.00₹1874.06

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Duocef 3gm Injection contains two active ingredients: Cefoperazone, a third-generation cephalosporin antibiotic, and Sulbactam, a beta-lactamase inhibitor. This combination provides coverage against a broad spectrum of bacteria and is used to treat serious infections including urinary tract infections, respiratory tract infections, intra-abdominal infections, septicemia, meningitis, skin infections, bone infections, and endometritis.

Duocef 3gm Injection is contraindicated in individuals with known hypersensitivity or allergy to it or its components. Inform your physician if you are allergic to any antibiotic group.

Consumption of alcohol (including alcoholic beverages, medications containing alcohol, mouthwashes, or food preparations) during and up to the fifth day after Duocef 3gm Injection administration can result in a disulfiram-like reaction, which may cause flushing, sweating, headache, and increased heart rate. Avoid alcohol during this period.

Notify your doctor if you experience severe or bloody stools while taking Duocef 3gm Injection. Before taking this medicine, discuss with your doctor if you have liver disorders, bowel diseases, or clotting disorders.

This drug should be used only if necessary during pregnancy. As this medicine passes poorly into breast milk, caution should be exercised during breastfeeding. Consult with your physician for further advice.

Uses

Duocef 3gm Injection uses in the treatment of the following: Respiratory Tract Infections Urinary Tract Infections Intra-abdominal Infections Septicemia Meningitis Skin and Soft Tissue Infections Bone and Joint Infections Endometritis

How it works

Duocef 3gm Injection is an antibiotic that works by interfering with bacterial cell wall synthesis, leading to the destruction of the bacteria. Sulbactam, the beta-lactamase inhibitor, helps inactivate the beta-lactamase enzymes produced by certain bacteria. These enzymes prevent the breakdown of cefoperazone, enhancing its effectiveness against resistant bacteria.

How to Use

Do not self-administer the Duocef 3gm Injection. Your doctor will decide the duration and dose of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion or intramuscular Injection, and you will be monitored carefully for unwanted side effects.

Side Effects

Duocef 3gm side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common side effects of Duocef 3gm Injection are: Nausea, vomiting Headache Diarrhea Allergic reactions Anemia Abnormal liver function Injection site reactions

References

  1. Pfizer Limited, [Revised on April 2020] [ Accessed on 27th June 2021], https://labeling.pfizer.com/ShowLabeling.aspx?id=14800
  2. Pfizer, US Food and Drug Administration, [Revised on March 2015] [ Accessed on 27th June 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf
  3. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Penicillins, cephalosporins, and other beta-lactam antibiotics, 12th edition, 2011, 1499.
  4. KD Tripathi, Essentials of Medical Pharmacology, Beta-lactam antibiotics, 7th edition, 2013, 728.

Safety Advice

Pregnancy: Consult Your Doctor Duocef 3gm Injection should be taken if necessary during pregnancy. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment.

Lungs: Consult Your Doctor It is unknown whether Duocef 3gm Injection is safe for patients with liver problems. Notify your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.

Breastfeeding: Unsafe Breastfeeding is not recommended in patients taking Duocef 3gm Injection because the medicine passes into the breast milk in small amounts and harms the baby. Caution is advised in these conditions.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS